Oxygen-dependent coproporphyrinogen-III oxidase, mitochondrial (COX) (Coprogen oxidase) (Coproporphyrinogenase) (EC 1.3.3.3)
1_MALQL 6_ GRLSS 11_ GPCWL 16_ VARGG 21_ CGGPR 26_ AWSQC 31_ GGGGL 36_ RAWSQ 41_ RSAAG 46_ RVCRP 51_ PGPAG 56_ TEQSR 61_ GLGHG 66_ STSRG 71_ GPWVG 76_ TGLAA 81_ ALAGL 86_ VGLAT 91_ AAFGH 96_ VQRAE 101_ MLPKT 106_ SGTRA 111_ TSLGR 116_ PEEEE 121_ DELAH 126_ RCSSF 131_ MAPPV 136_ TDLGE 141_ LRRRP 146_ GDMKT 151_ KMELL 156_ ILETQ 161_ AQVCQ 166_ ALAQV 171_ DGGAN 176_ FSVDR 181_ WERKE 186_ GGGGI 191_ SCVLQ 196_ DGCVF 201_ EKAGV 206_ SISVV 211_ HGNLS 216_ EEAAK 221_ QMRSR 226_ GKVLK 231_ TKDGK 236_ LPFCA 241_ MGVSS 246_ VIHPK 251_ NPHAP 256_ TIHFN 261_ YRYFE 266_ VEEAD 271_ GNKQW 276_ WFGGG 281_ CDLTP 286_ TYLNQ 291_ EDAVH 296_ FHRTL 301_ KEACD 306_ QHGPD 311_ LYPKF 316_ KKWCD 321_ DYFFI 326_ AHRGE 331_ RRGIG 336_ GIFFD 341_ DLDSP 346_ SKEEV 351_ FRFVQ 356_ SCARA 361_ VVPSY 366_ IPLVK 371_ KHCDD 376_ SFTPQ 381_ EKLWQ 386_ QLRRG 391_ RYVEF 396_ NLLYD 401_ RGTKF 406_ GLFTP 411_ GSRIE 416_ SILMS 421_ LPLTA 426_ RWEYM 431_ HSPSE 436_ NSKEA 441_ EILEV 446_LRHPR
1: Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX and participates to the sixth step in the heme biosynthetic pathway