Pigment epithelium-derived factor (PEDF) (Cell proliferation-inducing gene 35 protein) (EPC-1) (Serpin F1)
1_MQALV 6_ LLLCI 11_ GALLG 16_ HSSCQ 21_ NPASP 26_ PEEGS 31_ PDPDS 36_ TGALV 41_ EEEDP 46_ FFKVP 51_ VNKLA 56_ AAVSN 61_ FGYDL 66_ YRVRS 71_ STSPT 76_ TNVLL 81_ SPLSV 86_ ATALS 91_ ALSLG 96_ AEQRT 101_ ESIIH 106_ RALYY 111_ DLISS 116_ PDIHG 121_ TYKEL 126_ LDTVT 131_ APQKN 136_ LKSAS 141_ RIVFE 146_ KKLRI 151_ KSSFV 156_ APLEK 161_ SYGTR 166_ PRVLT 171_ GNPRL 176_ DLQEI 181_ NNWVQ 186_ AQMKG 191_ KLARS 196_ TKEIP 201_ DEISI 206_ LLLGV 211_ AHFKG 216_ QWVTK 221_ FDSRK 226_ TSLED 231_ FYLDE 236_ ERTVR 241_ VPMMS 246_ DPKAV 251_ LRYGL 256_ DSDLS 261_ CKIAQ 266_ LPLTG 271_ SMSII 276_ FFLPL 281_ KVTQN 286_ LTLIE 291_ ESLTS 296_ EFIHD 301_ IDREL 306_ KTVQA 311_ VLTVP 316_ KLKLS 321_ YEGEV 326_ TKSLQ 331_ EMKLQ 336_ SLFDS 341_ PDFSK 346_ ITGKP 351_ IKLTQ 356_ VEHRA 361_ GFEWN 366_ EDGAG 371_ TTPSP 376_ GLQPA 381_ HLTFP 386_ LDYHL 391_ NQPFI 396_ FVLRD 401_ TDTGA 406_ LLFIG 411_KILDP
1: Neurotrophic protein; induces extensive neuronal differentiation in retinoblastoma cells. Potent inhibitor of angiogenesis. As it does not undergo the S (stressed) to R (relaxed) conformational transition characteristic of active serpins, it exhibits no serine protease inhibitory activity