Zinc finger E-box-binding homeobox 1 (NIL-2-A zinc finger protein) (Negative regulator of IL2) (Transcription factor 8) (TCF-8)
1_MADGP 6_ RCKRR 11_ KQANP 16_ RRNNV 21_ TNYNT 26_ VVETN 31_ SDSDD 36_ EDKLH 41_ IVEEE 46_ SVTDA 51_ ADCEG 56_ VPEDD 61_ LPTDQ 66_ TVLPG 71_ RSSER 76_ EGNAK 81_ NCWED 86_ DRKEG 91_ QEILG 96_ PEAQA 101_ DEAGC 106_ TVKDD 111_ ECESD 116_ AENEQ 121_ NHDPN 126_ VEEFL 131_ QQQDT 136_ AVIFP 141_ EAPEE 146_ DQRQG 151_ TPEAS 156_ GHDEN 161_ GTPDA 166_ FSQLL 171_ TCPYC 176_ DRGYK 181_ RFTSL 186_ KEHIK 191_ YRHEK 196_ NEDNF 201_ SCSLC 206_ SYTFA 211_ YRTQL 216_ ERHMT 221_ SHKSG 226_ RDQRH 231_ VTQSG 236_ CNRKF 241_ KCTEC 246_ GKAFK 251_ YKHHL 256_ KEHLR 261_ IHSGE 266_ KPYEC 271_ PNCKK 276_ RFSHS 281_ GSYSS 286_ HISSK 291_ KCISL 296_ IPVNG 301_ RPRTG 306_ LKTSQ 311_ CSSPS 316_ LSASP 321_ GSPTR 326_ PQIRQ 331_ KIENK 336_ PLQEQ 341_ LSVNQ 346_ IKTEP 351_ VDYEF 356_ KPIVV 361_ ASGIN 366_ CSTPL 371_ QNGVF 376_ TGGGP 381_ LQATS 386_ SPQGM 391_ VQAVV 396_ LPTVG 401_ LVSPI 406_ SINLS 411_ DIQNV 416_ LKVAV 421_ DGNVI 426_ RQVLE 431_ NNQAN 436_ LASKE 441_ QETIN 446_ ASPIQ 451_ QGGHS 456_ VISAI 461_ SLPLV 466_ DQDGT 471_ TKIII 476_ NYSLE 481_ QPSQL 486_ QVVPQ 491_ NLKKE 496_ NPVAT 501_ NSCKS 506_ EKLPE 511_ DLTVK 516_ SEKDK 521_ SFEGG 526_ VNDST 531_ CLLCD 536_ DCPGD 541_ INALP 546_ ELKHY 551_ DLKQP 556_ TQPPP 561_ LPAAE 566_ AEKPE 571_ SSVSS 576_ ATGDG 581_ NLSPS 586_ QPPLK 591_ NLLSL 596_ LKAYY 601_ ALNAQ 606_ PSAEE 611_ LSKIA 616_ DSVNL 621_ PLDVV 626_ KKWFE 631_ KMQAG 636_ QISVQ 641_ SSEPS 646_ SPEPG 651_ KVNIP 656_ AKNND 661_ QPQSA 666_ NANEP 671_ QDSTV 676_ NLQSP 681_ LKMTN 686_ SPVLP 691_ VGSTT 696_ NGSRS 701_ STPSP 706_ SPLNL 711_ SSSRN 716_ TQGYL 721_ YTAEG 726_ AQEEP 731_ QVEPL 736_ DLSLP 741_ KQQGE 746_ LLERS 751_ TITSV 756_ YQNSV 761_ YSVQE 766_ EPLNL 771_ SCAKK 776_ EPQKD 781_ SCVTD 786_ SEPVV 791_ NVIPP 796_ SANPI 801_ NIAIP 806_ TVTAQ 811_ LPTIV 816_ AIADQ 821_ NSVPC 826_ LRALA 831_ ANKQT 836_ ILIPQ 841_ VAYTY 846_ STTVS 851_ PAVQE 856_ PPLKV 861_ IQPNG 866_ NQDER 871_ QDTSS 876_ EGVSN 881_ VEDQN 886_ DSDST 891_ PPKKK 896_ MRKTE 901_ NGMYA 906_ CDLCD 911_ KIFQK 916_ SSSLL 921_ RHKYE 926_ HTGKR 931_ PHECG 936_ ICKKA 941_ FKHKH 946_ HLIEH 951_ MRLHS 956_ GEKPY 961_ QCDKC 966_ GKRFS 971_ HSGSY 976_ SQHMN 981_ HRYSY 986_ CKREA 991_ EERDS 996_ TEQEE 1001_ AGPEI 1006_ LSNEH 1011_ VGARA 1016_ SPSQG 1021_ DSDER 1026_ ESLTR 1031_ EEDED 1036_ SEKEE 1041_ EEEDK 1046_ EMEEL 1051_ QEEKE 1056_ CEKPQ 1061_ GDEEE 1066_ EEEEE 1071_ EVEEE 1076_ EVEEA 1081_ ENEGE 1086_ EAKTE 1091_ GLMKD 1096_ DRAES 1101_ QASSL 1106_ GQKVG 1111_ ESSEQ 1116_VSEEK
1: Acts as a transcriptional repressor. Inhibits interleukin-2 (IL-2) gene expression. Enhances or represses the promoter activity of the ATP1A1 gene depending on the quantity of cDNA and on the cell type. Represses E-cadherin promoter and induces an epithelial-mesenchymal transition (EMT) by recruiting SMARCA4/BRG1. Represses BCL6 transcription in the presence of the corepressor CTBP1. Positively regulates neuronal differentiation. Represses RCOR1 transcription activation during neurogenesis. Represses transcription by binding to the E box (5'-CANNTG-3'). In the absence of TGFB1, acts as a repressor of COL1A2 transcription via binding to the E-box in the upstream enhancer region (By similarity)