Interferon gamma receptor 2 (IFN-gamma receptor 2) (IFN-gamma-R2) (Interferon gamma receptor accessory factor 1) (AF-1) (Interferon gamma receptor beta-chain) (IFN-gamma-R-beta) (Interferon gamma transducer 1)
1_MRPTL 6_ LWSLL 11_ LLLGV 16_ FAAAA 21_ AAPPD 26_ PLSQL 31_ PAPQH 36_ PKIRL 41_ YNAEQ 46_ VLSWE 51_ PVALS 56_ NSTRP 61_ VVYQV 66_ QFKYT 71_ DSKWF 76_ TADIM 81_ SIGVN 86_ CTQIT 91_ ATECD 96_ FTAAS 101_ PSAGF 106_ PMDFN 111_ VTLRL 116_ RAELG 121_ ALHSA 126_ WVTMP 131_ WFQHY 136_ RNVTV 141_ GPPEN 146_ IEVTP 151_ GEGSL 156_ IIRFS 161_ SPFDI 166_ ADTST 171_ AFFCY 176_ YVHYW 181_ EKGGI 186_ QQVKG 191_ PFRSN 196_ SISLD 201_ NLKPS 206_ RVYCL 211_ QVQAQ 216_ LLWNK 221_ SNIFR 226_ VGHLS 231_ NISCY 236_ ETMAD 241_ ASTEL 246_ QQVIL 251_ ISVGT 256_ FSLLS 261_ VLAGA 266_ CFFLV 271_ LKYRG 276_ LIKYW 281_ FHTPP 286_ SIPLQ 291_ IEEYL 296_ KDPTQ 301_ PILEA 306_ LDKDS 311_ SPKDD 316_ VWDSV 321_ SIISF 326_ PEKEQ 331_EDVLQ
1: Associates with IFNGR1 to form a receptor for the cytokine interferon gamma (IFNG) (PubMed:7615558, PubMed:7673114, PubMed:8124716). Ligand binding stimulates activation of the JAK/STAT signaling pathway (PubMed:15356148, PubMed:7673114, PubMed:8124716). Required for signal transduction in contrast to other receptor subunit responsible for ligand binding (PubMed:7673114)