Gene name: MPV17

Uniprot entry:

P39210

Protein names:

Protein Mpv17

Protein sequence:

1_MALWR 6_ AYQRA 11_ LAAHP 16_ WKVQV 21_ LTAGS 26_ LMGLG 31_ DIISQ 36_ QLVER 41_ RGLQE 46_ HQRGR 51_ TLTMV 56_ SLGCG 61_ FVGPV 66_ VGGWY 71_ KVLDR 76_ FIPGT 81_ TKVDA 86_ LKKML 91_ LDQGG 96_ FAPCF 101_ LGCFL 106_ PLVGA 111_ LNGLS 116_ AQDNW 121_ AKLQR 126_ DYPDA 131_ LITNY 136_ YLWPA 141_ VQLAN 146_ FYLVP 151_ LHYRL 156_ AVVQC 161_ VAVIW 166_ NSYLS 171_WKAHR

Protein annotations

Protein functions:

1: Non-selective channel that modulates the membrane potential under normal conditions and oxidative stress, and is involved in mitochondrial homeostasis (PubMed:25861990). Involved in mitochondrial deoxynucleoside triphosphates (dNTP) pool homeostasis and mitochondrial DNA (mtDNA) maintenance (PubMed:26760297). May be involved in the regulation of reactive oxygen species metabolism and the control of oxidative phosphorylation (By similarity)