Carcinoembryonic antigen-related cell adhesion molecule 3 (Carcinoembryonic antigen CGM1) (CD antigen CD66d)
1_MGPPS 6_ ASPHR 11_ ECIPW 16_ QGLLL 21_ TASLL 26_ NFWNP 31_ PTTAK 36_ LTIES 41_ MPLSV 46_ AEGKE 51_ VLLLV 56_ HNLPQ 61_ HLFGY 66_ SWYKG 71_ ERVDG 76_ NSLIV 81_ GYVIG 86_ TQQAT 91_ PGAAY 96_ SGRET 101_ IYTNA 106_ SLLIQ 111_ NVTQN 116_ DIGFY 121_ TLQVI 126_ KSDLV 131_ NEEAT 136_ GQFHV 141_ YQENA 146_ PGLPV 151_ GAVAG 156_ IVTGV 161_ LVGVA 166_ LVAAL 171_ VCFLL 176_ LAKTG 181_ RTSIQ 186_ RDLKE 191_ QQPQA 196_ LAPGR 201_ GPSHS 206_ SAFSM 211_ SPLST 216_ AQAPL 221_ PNPRT 226_ AASIY 231_ EELLK 236_ HDTNI 241_ YCRMD 246_HKAEV
1: Major granulocyte receptor mediating recognition and efficient opsonin-independent phagocytosis of CEACAM-binding microorganisms, including Neissiria, Moxarella and Haemophilus species, thus playing an important role in the clearance of pathogens by the innate immune system. Responsible for RAC1 stimulation in the course of pathogen phagocytosis