Gene name: CEACAM6

Uniprot entry:

P40199

Protein names:

Carcinoembryonic antigen-related cell adhesion molecule 6 (Non-specific crossreacting antigen) (Normal cross-reacting antigen) (CD antigen CD66c)

Protein sequence:

1_MGPPS 6_ APPCR 11_ LHVPW 16_ KEVLL 21_ TASLL 26_ TFWNP 31_ PTTAK 36_ LTIES 41_ TPFNV 46_ AEGKE 51_ VLLLA 56_ HNLPQ 61_ NRIGY 66_ SWYKG 71_ ERVDG 76_ NSLIV 81_ GYVIG 86_ TQQAT 91_ PGPAY 96_ SGRET 101_ IYPNA 106_ SLLIQ 111_ NVTQN 116_ DTGFY 121_ TLQVI 126_ KSDLV 131_ NEEAT 136_ GQFHV 141_ YPELP 146_ KPSIS 151_ SNNSN 156_ PVEDK 161_ DAVAF 166_ TCEPE 171_ VQNTT 176_ YLWWV 181_ NGQSL 186_ PVSPR 191_ LQLSN 196_ GNMTL 201_ TLLSV 206_ KRNDA 211_ GSYEC 216_ EIQNP 221_ ASANR 226_ SDPVT 231_ LNVLY 236_ GPDVP 241_ TISPS 246_ KANYR 251_ PGENL 256_ NLSCH 261_ AASNP 266_ PAQYS 271_ WFING 276_ TFQQS 281_ TQELF 286_ IPNIT 291_ VNNSG 296_ SYMCQ 301_ AHNSA 306_ TGLNR 311_ TTVTM 316_ ITVSG 321_ SAPVL 326_ SAVAT 331_ VGITI 336_GVLAR

Protein annotations

Protein functions:

1: Cell surface glycoprotein that plays a role in cell adhesion and tumor progression (PubMed:10910050, PubMed:11590190, PubMed:1378450, PubMed:16204051, PubMed:2022629, PubMed:2803308, PubMed:8776764). Intercellular adhesion occurs in a calcium- and fibronectin-independent manner (PubMed:16204051, PubMed:2022629). Mediates homophilic and heterophilic cell adhesion with other carcinoembryonic antigen-related cell adhesion molecules, such as CEACAM5 and CEACAM8 (PubMed:11590190, PubMed:16204051, PubMed:2022629, PubMed:2803308, PubMed:8776764). Heterophilic interaction with CEACAM8 occurs in activated neutrophils (PubMed:8776764). Plays a role in neutrophil adhesion to cytokine-activated endothelial cells (PubMed:1378450). Plays a role in cell migration and cell adhesion to endothelial cells (PubMed:16204051)