ADP-ribosylation factor-like protein 1
1_MGGFF 6_ SSIFS 11_ SLFGT 16_ REMRI 21_ LILGL 26_ DGAGK 31_ TTILY 36_ RLQVG 41_ EVVTT 46_ IPTIG 51_ FNVET 56_ VTYKN 61_ LKFQV 66_ WDLGG 71_ QTSIR 76_ PYWRC 81_ YYSNT 86_ DAVIY 91_ VVDSC 96_ DRDRI 101_ GISKS 106_ ELVAM 111_ LEEEE 116_ LRKAI 121_ LVVFA 126_ NKQDM 131_ EQAMT 136_ SSEMA 141_ NSLGL 146_ PALKD 151_ RKWQI 156_ FKTSA 161_ TKGTG 166_ LDEAM 171_ EWLVE 176_TLKSR
1: GTP-binding protein that recruits several effectors, such as golgins, arfaptins and Arf-GEFs to the trans-Golgi network, and modulates their functions at the Golgi complex (PubMed:21239483, PubMed:22679020, PubMed:27373159, PubMed:27436755, PubMed:9624189, PubMed:12972563). Plays thereby a role in a wide range of fundamental cellular processes, including cell polarity, innate immunity, or protein secretion mediated by arfaptins, which were shown to play a role in maintaining insulin secretion from pancreatic beta cells (PubMed:22981988)