Patatin-like phospholipase domain-containing protein 4 (EC 3.1.1.3) (Calcium-independent phospholipase A2-eta) (iPLA2-eta) (EC 3.1.1.4) (Protein GS2)
1_MKHIN 6_ LSFAA 11_ CGFLG 16_ IYHLG 21_ AASAL 26_ CRHGK 31_ KLVKD 36_ VKAFA 41_ GASAG 46_ SLVAS 51_ VLLTA 56_ PEKIE 61_ ECNQF 66_ TYKFA 71_ EEIRR 76_ QSFGA 81_ VTPGY 86_ DFMAR 91_ LRSGM 96_ ESILP 101_ PSAHE 106_ LAQNR 111_ LHVSI 116_ TNAKT 121_ RENHL 126_ VSTFS 131_ SREDL 136_ IKVLL 141_ ASSFV 146_ PIYAG 151_ LKLVE 156_ YKGQK 161_ WVDGG 166_ LTNAL 171_ PILPV 176_ GRTVT 181_ ISPFS 186_ GRLDI 191_ SPQDK 196_ GQLDL 201_ YVNIA 206_ KQDIM 211_ LSLAN 216_ LVRLN 221_ QALFP 226_ PSKRK 231_ MESLY 236_ QCGFD 241_ DTVKF 246_LLKEN
1: Has abundant triacylglycerol lipase activity (PubMed:15364929, PubMed:16150821, PubMed:17603008). Transfers fatty acid from triglyceride to retinol, hydrolyzes retinylesters, and generates 1,3-diacylglycerol from triglycerides (PubMed:17603008). Additionally possesses acylglycerol transacylase and phospholipase A2 activities (PubMed:15364929, PubMed:17603008)