Phosphatidylinositol 4-kinase alpha (PI4-kinase alpha) (PI4K-alpha) (PtdIns-4-kinase alpha) (EC 2.7.1.67) (Phosphatidylinositol 4-Kinase III alpha)
1_MAAAP 6_ ARGGG 11_ GGGGG 16_ GGGCS 21_ GSGSS 26_ ASRGF 31_ YFNTV 36_ LSLAR 41_ SLAVQ 46_ RPASL 51_ EKVQK 56_ LLCMC 61_ PVDFH 66_ GIFQL 71_ DERRR 76_ DAVIA 81_ LGIFL 86_ IESDL 91_ QHKDC 96_ VVPYL 101_ LRLLK 106_ GLPKV 111_ YWVEE 116_ STARK 121_ GRGAL 126_ PVAES 131_ FSFCL 136_ VTLLS 141_ DVAYR 146_ DPSLR 151_ DEILE 156_ VLLQV 161_ LHVLL 166_ GMCQA 171_ LEIQD 176_ KEYLC 181_ KYAIP 186_ CLIGI 191_ SRAFG 196_ RYSNM 201_ EESLL 206_ SKLFP 211_ KIPPH 216_ SLRVL 221_ EELEG 226_ VRRRS 231_ FNDFR 236_ SILPS 241_ NLLTV 246_ CQEGT 251_ LKRKT 256_ SSVSS 261_ ISQVS 266_ PERGM 271_ PPPSS 276_ PGGSA 281_ FHYFE 286_ ASCLP 291_ DGTAL 296_ EPEYY 301_ FSTIS 306_ SSFSV 311_ SPLFN 316_ GVTYK 321_ EFNIP 326_ LEMLR 331_ ELLNL 336_ VKKIV 341_ EEAVL 346_ KSLDA 351_ IVASV 356_ MEANP 361_ SADLY 366_ YTSFS 371_ DPLYL 376_ TMFKM 381_ LRDTL 386_ YYMKD 391_ LPTSF 396_ VKEIH 401_ DFVLE 406_ QFNTS 411_ QGELQ 416_ KILHD 421_ ADRIH 426_ NELSP 431_ LKLRC 436_ QANAA 441_ CVDLM 446_ VWAVK 451_ DEQGA 456_ ENLCI 461_ KLSEK 466_ LQSKT 471_ SSKVI 476_ IAHLP 481_ LLICC 486_ LQGLG 491_ RLCER 496_ FPVVV 501_ HSVTP 506_ SLRDF 511_ LVIPS 516_ PVLVK 521_ LYKYH 526_ SQYHT 531_ VAGND 536_ IKISV 541_ TNEHS 546_ ESTLN 551_ VMSGK 556_ KSQPS 561_ MYEQL 566_ RDIAI 571_ DNICR 576_ CLKAG 581_ LTVDP 586_ VIVEA 591_ FLASL 596_ SNRLY 601_ ISQES 606_ DKDAH 611_ LIPDH 616_ TIRAL 621_ GHIAV 626_ ALRDT 631_ PKVME 636_ PILQI 641_ LQQKF 646_ CQPPS 651_ PLDVL 656_ IIDQL 661_ GCLVI 666_ TGNQY 671_ IYQEV 676_ WNLFQ 681_ QISVK 686_ ASSVV 691_ YSATK 696_ DYKDH 701_ GYRHC 706_ SLAVI 711_ NALAN 716_ IAANI 721_ QDEHL 726_ VDELL 731_ MNLLE 736_ LFVQL 741_ GLEGK 746_ RASER 751_ ASEKG 756_ PALKA 761_ SSSAG 766_ NLGVL 771_ IPVIA 776_ VLTRR 781_ LPPIK 786_ EAKPR 791_ LQKLF 796_ RDFWL 801_ YSVLM 806_ GFAVE 811_ GSGLW 816_ PEEWY 821_ EGVCE 826_ IATKS 831_ PLLTF 836_ PSKEP 841_ LRSVL 846_ QYNSA 851_ MKNDT 856_ VTPAE 861_ LSELR 866_ STIIN 871_ LLDPP 876_ PEVSA 881_ LINKL 886_ DFAMS 891_ TYLLS 896_ VYRLE 901_ YMRVL 906_ RSTDP 911_ DRFQV 916_ MFCYF 921_ EDKAI 926_ QKDKS 931_ GMMQC 936_ VIAVA 941_ DKVFD 946_ AFLNM 951_ MADKA 956_ KTKEN 961_ EEELE 966_ RHAQF 971_ LLVNF 976_ NHIHK 981_ RIRRV 986_ ADKYL 991_ SGLVD 996_ KFPHL 1001_ LWSGT 1006_ VLKTM 1011_ LDILQ 1016_ TLSLS 1021_ LSADI 1026_ HKDQP 1031_ YYDIP 1036_ DAPYR 1041_ ITVPD 1046_ TYEAR 1051_ ESIVK 1056_ DFAAR 1061_ CGMIL 1066_ QEAMK 1071_ WAPTV 1076_ TKSHL 1081_ QEYLN 1086_ KHQNW 1091_ VSGLS 1096_ QHTGL 1101_ AMATE 1106_ SILHF 1111_ AGYNK 1116_ QNTTL 1121_ GATQL 1126_ SERPA 1131_ CVKKD 1136_ YSNFM 1141_ ASLNL 1146_ RNRYA 1151_ GEVYG 1156_ MIRFS 1161_ GTTGQ 1166_ MSDLN 1171_ KMMVQ 1176_ DLHSA 1181_ LDRSH 1186_ PQHYT 1191_ QAMFK 1196_ LTAML 1201_ ISSKD 1206_ CDPQL 1211_ LHHLC 1216_ WGPLR 1221_ MFNEH 1226_ GMETA 1231_ LACWE 1236_ WLLAG 1241_ KDGVE 1246_ VPFMR 1251_ EMAGA 1256_ WHMTV 1261_ EQKFG 1266_ LFSAE 1271_ IKEAD 1276_ PLAAS 1281_ EASQP 1286_ KPCPP 1291_ EVTPH 1296_ YIWID 1301_ FLVQR 1306_ FEIAK 1311_ YCSSD 1316_ QVEIF 1321_ SSLLQ 1326_ RSMSL 1331_ NIGGA 1336_ KGSMN 1341_ RHVAA 1346_ IGPRF 1351_ KLLTL 1356_ GLSLL 1361_ HADVV 1366_ PNATI 1371_ RNVLR 1376_ EKIYS 1381_ TAFDY 1386_ FSCPP 1391_ KFPTQ 1396_ GEKRL 1401_ REDIS 1406_ IMIKF 1411_ WTAMF 1416_ SDKKY 1421_ LTASQ 1426_ LVPPD 1431_ NQDTR 1436_ SNLDI 1441_ TVGSR 1446_ QQATQ 1451_ GWINT 1456_ YPLSS 1461_ GMSTI 1466_ SKKSG 1471_ MSKKT 1476_ NRGSQ 1481_ LHKYY 1486_ MKRRT 1491_ LLLSL 1496_ LATEI 1501_ ERLIT 1506_ WYNPL 1511_ SAPEL 1516_ ELDQA 1521_ GENSV 1526_ ANWRS 1531_ KYISL 1536_ SEKQW 1541_ KDNVN 1546_ LAWSI 1551_ SPYLA 1556_ VQLPA 1561_ RFKNT 1566_ EAIGN 1571_ EVTRL 1576_ VRLDP 1581_ GAVSD 1586_ VPEAI 1591_ KFLVT 1596_ WHTID 1601_ ADAPE 1606_ LSHVL 1611_ CWAPT 1616_ DPPTG 1621_ LSYFS 1626_ SMYPP 1631_ HPLTA 1636_ QYGVK 1641_ VLRSF 1646_ PPDAI 1651_ LFYIP 1656_ QIVQA 1661_ LRYDK 1666_ MGYVR 1671_ EYILW 1676_ AASKS 1681_ QLLAH 1686_ QFIWN 1691_ MKTNI 1696_ YLDEE 1701_ GHQKD 1706_ PDIGD 1711_ LLDQL 1716_ VEEIT 1721_ GSLSG 1726_ PAKDF 1731_ YQREF 1736_ DFFNK 1741_ ITNVS 1746_ AIIKP 1751_ YPKGD 1756_ ERKKA 1761_ CLSAL 1766_ SEVKV 1771_ QPGCY 1776_ LPSNP 1781_ EAIVL 1786_ DIDYK 1791_ SGTPM 1796_ QSAAK 1801_ APYLA 1806_ KFKVK 1811_ RCGVS 1816_ ELEKE 1821_ GLRCR 1826_ SDSED 1831_ ECSTQ 1836_ EADGQ 1841_ KISWQ 1846_ AAIFK 1851_ VGDDC 1856_ RQDML 1861_ ALQII 1866_ DLFKN 1871_ IFQLV 1876_ GLDLF 1881_ VFPYR 1886_ VVATA 1891_ PGCGV 1896_ IECIP 1901_ DCTSR 1906_ DQLGR 1911_ QTDFG 1916_ MYDYF 1921_ TRQYG 1926_ DESTL 1931_ AFQQA 1936_ RYNFI 1941_ RSMAA 1946_ YSLLL 1951_ FLLQI 1956_ KDRHN 1961_ GNIML 1966_ DKKGH 1971_ IIHID 1976_ FGFMF 1981_ ESSPG 1986_ GNLGW 1991_ EPDIK 1996_ LTDEM 2001_ VMIMG 2006_ GKMEA 2011_ TPFKW 2016_ FMEMC 2021_ VRGYL 2026_ AVRPY 2031_ MDAVV 2036_ SLVTL 2041_ MLDTG 2046_ LPCFR 2051_ GQTIK 2056_ LLKHR 2061_ FSPNM 2066_ TEREA 2071_ ANFIM 2076_ KVIQS 2081_ CFLSN 2086_ RSRTY 2091_ DMIQY 2096_YQNDI
1: Acts on phosphatidylinositol (PtdIns) in the first committed step in the production of the second messenger inositol-1,4,5,-trisphosphate