Condensin-2 complex subunit D3 (Non-SMC condensin II complex subunit D3) (hCAP-D3)
1_MVALR 6_ GLGSG 11_ LQPWC 16_ PLDLR 21_ LEWVD 26_ TVWEL 31_ DFTET 36_ EPLDP 41_ SIEAE 46_ IIETG 51_ LAAFT 56_ KLYES 61_ LLPFA 66_ TGEHG 71_ SMESI 76_ WTFFI 81_ ENNVS 86_ HSTLV 91_ ALFYH 96_ FVQIV 101_ HKKNV 106_ SVQYR 111_ EYGLH 116_ AAGLY 121_ FLLLE 126_ VPGSV 131_ ANQVF 136_ HPVMF 141_ DKCIQ 146_ TLKKS 151_ WPQES 156_ NLNRK 161_ RKKEQ 166_ PKSSQ 171_ ANPGR 176_ HRKRG 181_ KPPRR 186_ EDIEM 191_ DEIIE 196_ EQEDE 201_ NICFS 206_ ARDLS 211_ QIRNA 216_ IFHLL 221_ KNFLR 226_ LLPKF 231_ SLKEK 236_ PQCVQ 241_ NCIEV 246_ FVSLT 251_ NFEPV 256_ LHECH 261_ VTQAR 266_ ALNQA 271_ KYIPE 276_ LAYYG 281_ LYLLC 286_ SPIHG 291_ EGDKV 296_ ISCVF 301_ HQMLS 306_ VILML 311_ EVGEG 316_ SHRAP 321_ LAVTS 326_ QVINC 331_ RNQAV 336_ QFISA 341_ LVDEL 346_ KESIF 351_ PVVRI 356_ LLQHI 361_ CAKVV 366_ DKSEY 371_ RTFAA 376_ QSLVQ 381_ LLSKL 386_ PCGEY 391_ AMFIA 396_ WLYKY 401_ SRSSK 406_ IPHRV 411_ FTLDV 416_ VLALL 421_ ELPER 426_ EVDNT 431_ LSLEH 436_ QKFLK 441_ HKFLV 446_ QEIMF 451_ DRCLD 456_ KAPTV 461_ RSKAL 466_ SSFAH 471_ CLELT 476_ VTSAS 481_ ESILE 486_ LLINS 491_ PTFSV 496_ IESHP 501_ GTLLR 506_ NSSAF 511_ SYQRQ 516_ TSNRS 521_ EPSGE 526_ INIDS 531_ SGETV 536_ GSGER 541_ CVMAM 546_ LRRRI 551_ RDEKT 556_ NVRKS 561_ ALQVL 566_ VSILK 571_ HCDVS 576_ GMKED 581_ LWILQ 586_ DQCRD 591_ PAVSV 596_ RKQAL 601_ QSLTE 606_ LLMAQ 611_ PRCVQ 616_ IQKAW 621_ LRGVV 626_ PVVMD 631_ CESTV 636_ QEKAL 641_ EFLDQ 646_ LLLQN 651_ IRHHS 656_ HFHSG 661_ DDSQV 666_ LAWAL 671_ LTLLT 676_ TESQE 681_ LSRYL 686_ NKAFH 691_ IWSKK 696_ EKFSP 701_ TFINN 706_ VISHT 711_ GTEHS 716_ APAWM 721_ LLSKI 726_ AGSSP 731_ RLDYS 736_ RIIQS 741_ WEKIS 746_ SQQNP 751_ NSNTL 756_ GHILC 761_ VIGHI 766_ AKHLP 771_ KSTRD 776_ KVTDA 781_ VKCKL 786_ NGFQW 791_ SLEVI 796_ SSAVD 801_ ALQRL 806_ CRASA 811_ ETPAE 816_ EQELL 821_ TQVCG 826_ DVLST 831_ CEHRL 836_ SNIVL 841_ KENGT 846_ GNMDE 851_ DLLVK 856_ YIFTL 861_ GDIAQ 866_ LCPAR 871_ VEKRI 876_ FLLIQ 881_ SVLAS 886_ SADAD 891_ HSPSS 896_ QGSSE 901_ APASQ 906_ PPPQV 911_ RGSVM 916_ PSVIR 921_ AHAII 926_ TLGKL 931_ CLQHE 936_ DLAKK 941_ SIPAL 946_ VRELE 951_ VCEDV 956_ AVRNN 961_ VIIVM 966_ CDLCI 971_ RYTIM 976_ VDKYI 981_ PNISM 986_ CLKDS 991_ DPFIR 996_ KQTLI 1001_ LLTNL 1006_ LQEEF 1011_ VKWKG 1016_ SLFFR 1021_ FVSTL 1026_ IDSHP 1031_ DIASF 1036_ GEFCL 1041_ AHLLL 1046_ KRNPV 1051_ MFFQH 1056_ FIECI 1061_ FHFNN 1066_ YEKHE 1071_ KYNKF 1076_ PQSER 1081_ EKRLF 1086_ SLKGK 1091_ SNKER 1096_ RMKIY 1101_ KFLLE 1106_ HFTDE 1111_ QRFNI 1116_ TSKIC 1121_ LSILA 1126_ CFADG 1131_ ILPLD 1136_ LDASE 1141_ LLSDT 1146_ FEVLS 1151_ SKEIK 1156_ LLAMR 1161_ SKPDK 1166_ DLLME 1171_ EDDMA 1176_ LANVV 1181_ MQEAQ 1186_ KKLIS 1191_ QVQKR 1196_ NFIEN 1201_ IIPII 1206_ ISLKT 1211_ VLEKN 1216_ KIPAL 1221_ RELMH 1226_ YLREV 1231_ MQDYR 1236_ DELKD 1241_ FFAVD 1246_ KQLAS 1251_ ELEYD 1256_ MKKYQ 1261_ EQLVQ 1266_ EQELA 1271_ KHADV 1276_ AGTAG 1281_ GAEVA 1286_ PVAQV 1291_ ALCLE 1296_ TVPVP 1301_ AGQEN 1306_ PAMSP 1311_ AVSQP 1316_ CTPRA 1321_ SAGHV 1326_ AVSSP 1331_ TPETG 1336_ PLQRL 1341_ LPKAR 1346_ PMSLS 1351_ TIAIL 1356_ NSVKK 1361_ AVESK 1366_ SRHRS 1371_ RSLGV 1376_ LPFTL 1381_ NSGSP 1386_ EKTCS 1391_ QVSSY 1396_ SLEQE 1401_ SNGEI 1406_ EHVTK 1411_ RAIST 1416_ PEKSI 1421_ SDVTF 1426_ GAGVS 1431_ YIGTP 1436_ RTPSS 1441_ AKEKI 1446_ EGRSQ 1451_ GNDIL 1456_ CLSLP 1461_ DKPPP 1466_ QPQQW 1471_ NVRSP 1476_ ARNKD 1481_ TPACS 1486_ RRSLR 1491_KTPLK
1: Regulatory subunit of the condensin-2 complex, a complex which establishes mitotic chromosome architecture and is involved in physical rigidity of the chromatid axis (PubMed:14532007). May promote the resolution of double-strand DNA catenanes (intertwines) between sister chromatids. Condensin-mediated compaction likely increases tension in catenated sister chromatids, providing directionality for type II topoisomerase-mediated strand exchanges toward chromatid decatenation. Specifically required for decatenation of centromeric ultrafine DNA bridges during anaphase. Early in neurogenesis, may play an essential role to ensure accurate mitotic chromosome condensation in neuron stem cells, ultimately affecting neuron pool and cortex size (PubMed:27737959)