Gene name: CDKN2C

Uniprot entry:

P42773

Protein names:

Cyclin-dependent kinase 4 inhibitor C (Cyclin-dependent kinase 6 inhibitor) (p18-INK4c) (p18-INK6)

Protein sequence:

1_MAEPW 6_ GNELA 11_ SAAAR 16_ GDLEQ 21_ LTSLL 26_ QNNVN 31_ VNAQN 36_ GFGRT 41_ ALQVM 46_ KLGNP 51_ EIARR 56_ LLLRG 61_ ANPDL 66_ KDRTG 71_ FAVIH 76_ DAARA 81_ GFLDT 86_ LQTLL 91_ EFQAD 96_ VNIED 101_ NEGNL 106_ PLHLA 111_ AKEGH 116_ LRVVE 121_ FLVKH 126_ TASNV 131_ GHRNH 136_ KGDTA 141_ CDLAR 146_ LYGRN 151_ EVVSL 156_ MQANG 161_AGGAT

Protein annotations

Protein functions:

1: Interacts strongly with CDK6, weakly with CDK4. Inhibits cell growth and proliferation with a correlated dependence on endogenous retinoblastoma protein RB