Excitatory amino acid transporter 1 (Sodium-dependent glutamate/aspartate transporter 1) (GLAST-1) (Solute carrier family 1 member 3)
1_MTKSN 6_ GEEPK 11_ MGGRM 16_ ERFQQ 21_ GVRKR 26_ TLLAK 31_ KKVQN 36_ ITKED 41_ VKSYL 46_ FRNAF 51_ VLLTV 56_ TAVIV 61_ GTILG 66_ FTLRP 71_ YRMSY 76_ REVKY 81_ FSFPG 86_ ELLMR 91_ MLQML 96_ VLPLI 101_ ISSLV 106_ TGMAA 111_ LDSKA 116_ SGKMG 121_ MRAVV 126_ YYMTT 131_ TIIAV 136_ VIGII 141_ IVIII 146_ HPGKG 151_ TKENM 156_ HREGK 161_ IVRVT 166_ AADAF 171_ LDLIR 176_ NMFPP 181_ NLVEA 186_ CFKQF 191_ KTNYE 196_ KRSFK 201_ VPIQA 206_ NETLV 211_ GAVIN 216_ NVSEA 221_ METLT 226_ RITEE 231_ LVPVP 236_ GSVNG 241_ VNALG 246_ LVVFS 251_ MCFGF 256_ VIGNM 261_ KEQGQ 266_ ALREF 271_ FDSLN 276_ EAIMR 281_ LVAVI 286_ MWYAP 291_ VGILF 296_ LIAGK 301_ IVEME 306_ DMGVI 311_ GGQLA 316_ MYTVT 321_ VIVGL 326_ LIHAV 331_ IVLPL 336_ LYFLV 341_ TRKNP 346_ WVFIG 351_ GLLQA 356_ LITAL 361_ GTSSS 366_ SATLP 371_ ITFKC 376_ LEENN 381_ GVDKR 386_ VTRFV 391_ LPVGA 396_ TINMD 401_ GTALY 406_ EALAA 411_ IFIAQ 416_ VNNFE 421_ LNFGQ 426_ IITIS 431_ ITATA 436_ ASIGA 441_ AGIPQ 446_ AGLVT 451_ MVIVL 456_ TSVGL 461_ PTDDI 466_ TLIIA 471_ VDWFL 476_ DRLRT 481_ TTNVL 486_ GDSLG 491_ AGIVE 496_ HLSRH 501_ ELKNR 506_ DVEMG 511_ NSVIE 516_ ENEMK 521_ KPYQL 526_ IAQDN 531_ ETEKP 536_IDSET
1: Sodium-dependent, high-affinity amino acid transporter that mediates the uptake of L-glutamate and also L-aspartate and D-aspartate (PubMed:20477940, PubMed:26690923, PubMed:28032905, PubMed:28424515, PubMed:7521911, PubMed:8123008). Functions as a symporter that transports one amino acid molecule together with two or three Na(+) ions and one proton, in parallel with the counter-transport of one K(+) ion (PubMed:20477940). Mediates Cl(-) flux that is not coupled to amino acid transport; this avoids the accumulation of negative charges due to aspartate and Na(+) symport (PubMed:20477940). Plays a redundant role in the rapid removal of released glutamate from the synaptic cleft, which is essential for terminating the postsynaptic action of glutamate (By similarity)