Excitatory amino acid transporter 2 (Glutamate/aspartate transporter II) (Sodium-dependent glutamate/aspartate transporter 2) (Solute carrier family 1 member 2)
1_MASTE 6_ GANNM 11_ PKQVE 16_ VRMHD 21_ SHLGS 26_ EEPKH 31_ RHLGL 36_ RLCDK 41_ LGKNL 46_ LLTLT 51_ VFGVI 56_ LGAVC 61_ GGLLR 66_ LASPI 71_ HPDVV 76_ MLIAF 81_ PGDIL 86_ MRMLK 91_ MLILP 96_ LIISS 101_ LITGL 106_ SGLDA 111_ KASGR 116_ LGTRA 121_ MVYYM 126_ STTII 131_ AAVLG 136_ VILVL 141_ AIHPG 146_ NPKLK 151_ KQLGP 156_ GKKND 161_ EVSSL 166_ DAFLD 171_ LIRNL 176_ FPENL 181_ VQACF 186_ QQIQT 191_ VTKKV 196_ LVAPP 201_ PDEEA 206_ NATSA 211_ VVSLL 216_ NETVT 221_ EVPEE 226_ TKMVI 231_ KKGLE 236_ FKDGM 241_ NVLGL 246_ IGFFI 251_ AFGIA 256_ MGKMG 261_ DQAKL 266_ MVDFF 271_ NILNE 276_ IVMKL 281_ VIMIM 286_ WYSPL 291_ GIACL 296_ ICGKI 301_ IAIKD 306_ LEVVA 311_ RQLGM 316_ YMVTV 321_ IIGLI 326_ IHGGI 331_ FLPLI 336_ YFVVT 341_ RKNPF 346_ SFFAG 351_ IFQAW 356_ ITALG 361_ TASSA 366_ GTLPV 371_ TFRCL 376_ EENLG 381_ IDKRV 386_ TRFVL 391_ PVGAT 396_ INMDG 401_ TALYE 406_ AVAAI 411_ FIAQM 416_ NGVVL 421_ DGGQI 426_ VTVSL 431_ TATLA 436_ SVGAA 441_ SIPSA 446_ GLVTM 451_ LLILT 456_ AVGLP 461_ TEDIS 466_ LLVAV 471_ DWLLD 476_ RMRTS 481_ VNVVG 486_ DSFGA 491_ GIVYH 496_ LSKSE 501_ LDTID 506_ SQHRV 511_ HEDIE 516_ MTKTQ 521_ SIYDD 526_ MKNHR 531_ ESNSN 536_ QCVYA 541_ AHNSV 546_ IVDEC 551_ KVTLA 556_ ANGKS 561_ ADCSV 566_EEEPW
1: Sodium-dependent, high-affinity amino acid transporter that mediates the uptake of L-glutamate and also L-aspartate and D-aspartate (PubMed:14506254, PubMed:15265858, PubMed:26690923, PubMed:7521911). Functions as a symporter that transports one amino acid molecule together with two or three Na(+) ions and one proton, in parallel with the counter-transport of one K(+) ion (PubMed:14506254). Mediates Cl(-) flux that is not coupled to amino acid transport; this avoids the accumulation of negative charges due to aspartate and Na(+) symport (PubMed:14506254). Essential for the rapid removal of released glutamate from the synaptic cleft, and for terminating the postsynaptic action of glutamate (By similarity)