Prostaglandin F2-alpha receptor (PGF receptor) (PGF2-alpha receptor) (Prostanoid FP receptor)
1_MSMNN 6_ SKQLV 11_ SPAAA 16_ LLSNT 21_ TCQTE 26_ NRLSV 31_ FFSVI 36_ FMTVG 41_ ILSNS 46_ LAIAI 51_ LMKAY 56_ QRFRQ 61_ KSKAS 66_ FLLLA 71_ SGLVI 76_ TDFFG 81_ HLING 86_ AIAVF 91_ VYASD 96_ KEWIR 101_ FDQSN 106_ VLCSI 111_ FGICM 116_ VFSGL 121_ CPLLL 126_ GSVMA 131_ IERCI 136_ GVTKP 141_ IFHST 146_ KITSK 151_ HVKMM 156_ LSGVC 161_ LFAVF 166_ IALLP 171_ ILGHR 176_ DYKIQ 181_ ASRTW 186_ CFYNT 191_ EDIKD 196_ WEDRF 201_ YLLLF 206_ SFLGL 211_ LALGV 216_ SLLCN 221_ AITGI 226_ TLLRV 231_ KFKSQ 236_ QHRQG 241_ RSHHL 246_ EMVIQ 251_ LLAIM 256_ CVSCI 261_ CWSPF 266_ LVTMA 271_ NIGIN 276_ GNHSL 281_ ETCET 286_ TLFAL 291_ RMATW 296_ NQILD 301_ PWVYI 306_ LLRKA 311_ VLKNL 316_ YKLAS 321_ QCCGV 326_ HVISL 331_ HIWEL 336_ SSIKN 341_ SLKVA 346_ AISES 351_PVAEK
1: Receptor for prostaglandin F2-alpha (PGF2-alpha). The activity of this receptor is mediated by G proteins which activate a phosphatidylinositol-calcium second messenger system. Initiates luteolysis in the corpus luteum (By similarity). Isoforms 2 to 7 do not bind PGF2-alpha but are proposed to modulate signaling by participating in variant receptor complexes; heterodimers between isoform 1 and isoform 5 are proposed to be a receptor for prostamides including the synthetic analog bimatoprost