Matrin-3
1_MSKSF 6_ QQSSL 11_ SRDSQ 16_ GHGRD 21_ LSAAG 26_ IGLLA 31_ AATQS 36_ LSMPA 41_ SLGRM 46_ NQGTA 51_ RLASL 56_ MNLGM 61_ SSSLN 66_ QQGAH 71_ SALSS 76_ ASTSS 81_ HNLQS 86_ IFNIG 91_ SRGPL 96_ PLSSQ 101_ HRGDA 106_ DQASN 111_ ILASF 116_ GLSAR 121_ DLDEL 126_ SRYPE 131_ DKITP 136_ ENLPQ 141_ ILLQL 146_ KRRRT 151_ EEGPT 156_ LSYGR 161_ DGRSA 166_ TREPP 171_ YRVPR 176_ DDWEE 181_ KRHFR 186_ RDSFD 191_ DRGPS 196_ LNPVL 201_ DYDHG 206_ SRSQE 211_ SGYYD 216_ RMDYE 221_ DDRLR 226_ DGERC 231_ RDDSF 236_ FGETS 241_ HNYHK 246_ FDSEY 251_ ERMGR 256_ GPGPL 261_ QERSL 266_ FEKKR 271_ GAPPS 276_ SNIED 281_ FHGLL 286_ PKGYP 291_ HLCSI 296_ CDLPV 301_ HSNKE 306_ WSQHI 311_ NGASH 316_ SRRCQ 321_ LLLEI 326_ YPEWN 331_ PDNDT 336_ GHTMG 341_ DPFML 346_ QQSTN 351_ PAPGI 356_ LGPPP 361_ PSFHL 366_ GGPAV 371_ GPRGN 376_ LGAGN 381_ GNLQG 386_ PRHMQ 391_ KGRVE 396_ TSRVV 401_ HIMDF 406_ QRGKN 411_ LRYQL 416_ LQLVE 421_ PFGVI 426_ SNHLI 431_ LNKIN 436_ EAFIE 441_ MATTE 446_ DAQAA 451_ VDYYT 456_ TTPAL 461_ VFGKP 466_ VRVHL 471_ SQKYK 476_ RIKKP 481_ EGKPD 486_ QKFDQ 491_ KQELG 496_ RVIHL 501_ SNLPH 506_ SGYSD 511_ SAVLK 516_ LAEPY 521_ GKIKN 526_ YILMR 531_ MKSQA 536_ FIEME 541_ TREDA 546_ MAMVD 551_ HCLKK 556_ ALWFQ 561_ GRCVK 566_ VDLSE 571_ KYKKL 576_ VLRIP 581_ NRGID 586_ LLKKD 591_ KSRKR 596_ SYSPD 601_ GKESP 606_ SDKKS 611_ KTDGS 616_ QKTES 621_ STEGK 626_ EQEEK 631_ SGEDG 636_ EKDTK 641_ DDQTE 646_ QEPNM 651_ LLESE 656_ DELLV 661_ DEEEA 666_ AALLE 671_ SGSSV 676_ GDETD 681_ LANLG 686_ DVASD 691_ GKKEP 696_ SDKAV 701_ KKDGS 706_ ASAAA 711_ KKKLK 716_ KVDKI 721_ EELDQ 726_ ENEAA 731_ LENGI 736_ KNEEN 741_ TEPGA 746_ ESSEN 751_ ADDPN 756_ KDTSE 761_ NADGQ 766_ SDENK 771_ DDYTI 776_ PDEYR 781_ IGPYQ 786_ PNVPV 791_ GIDYV 796_ IPKTG 801_ FYCKL 806_ CSLFY 811_ TNEEV 816_ AKNTH 821_ CSSLP 826_ HYQKL 831_ KKFLN 836_ KLAEE 841_RRQKK
1: May play a role in transcription or may interact with other nuclear matrix proteins to form the internal fibrogranular network. In association with the SFPQ-NONO heteromer may play a role in nuclear retention of defective RNAs. Plays a role in the regulation of DNA virus-mediated innate immune response by assembling into the HDP-RNP complex, a complex that serves as a platform for IRF3 phosphorylation and subsequent innate immune response activation through the cGAS-STING pathway (PubMed:28712728). Binds to N6-methyladenosine (m6A)-containing mRNAs and contributes to MYC stability by binding to m6A-containing MYC mRNAs (PubMed:32245947). May bind to specific miRNA hairpins (PubMed:28431233)