Vesicle-fusing ATPase (EC 3.6.4.6) (N-ethylmaleimide-sensitive fusion protein) (NEM-sensitive fusion protein) (Vesicular-fusion protein NSF)
1_MAGRS 6_ MQAAR 11_ CPTDE 16_ LSLTN 21_ CAVVN 26_ EKDFQ 31_ SGQHV 36_ IVRTS 41_ PNHRY 46_ TFTLK 51_ THPSV 56_ VPGSI 61_ AFSLP 66_ QRKWA 71_ GLSIG 76_ QEIEV 81_ SLYTF 86_ DKAKQ 91_ CIGTM 96_ TIEID 101_ FLQKK 106_ SIDSN 111_ PYDTD 116_ KMAAE 121_ FIQQF 126_ NNQAF 131_ SVGQQ 136_ LVFSF 141_ NEKLF 146_ GLLVK 151_ DIEAM 156_ DPSIL 161_ KGEPA 166_ TGKRQ 171_ KIEVG 176_ LVVGN 181_ SQVAF 186_ EKAEN 191_ SSLNL 196_ IGKAK 201_ TKENR 206_ QSIIN 211_ PDWNF 216_ EKMGI 221_ GGLDK 226_ EFSDI 231_ FRRAF 236_ ASRVF 241_ PPEIV 246_ EQMGC 251_ KHVKG 256_ ILLYG 261_ PPGCG 266_ KTLLA 271_ RQIGK 276_ MLNAR 281_ EPKVV 286_ NGPEI 291_ LNKYV 296_ GESEA 301_ NIRKL 306_ FADAE 311_ EEQRR 316_ LGANS 321_ GLHII 326_ IFDEI 331_ DAICK 336_ QRGSM 341_ AGSTG 346_ VHDTV 351_ VNQLL 356_ SKIDG 361_ VEQLN 366_ NILVI 371_ GMTNR 376_ PDLID 381_ EALLR 386_ PGRLE 391_ VKMEI 396_ GLPDE 401_ KGRLQ 406_ ILHIH 411_ TARMR 416_ GHQLL 421_ SADVD 426_ IKELA 431_ VETKN 436_ FSGAE 441_ LEGLV 446_ RAAQS 451_ TAMNR 456_ HIKAS 461_ TKVEV 466_ DMEKA 471_ ESLQV 476_ TRGDF 481_ LASLE 486_ NDIKP 491_ AFGTN 496_ QEDYA 501_ SYIMN 506_ GIIKW 511_ GDPVT 516_ RVLDD 521_ GELLV 526_ QQTKN 531_ SDRTP 536_ LVSVL 541_ LEGPP 546_ HSGKT 551_ ALAAK 556_ IAEES 561_ NFPFI 566_ KICSP 571_ DKMIG 576_ FSETA 581_ KCQAM 586_ KKIFD 591_ DAYKS 596_ QLSCV 601_ VVDDI 606_ ERLLD 611_ YVPIG 616_ PRFSN 621_ LVLQA 626_ LLVLL 631_ KKAPP 636_ QGRKL 641_ LIIGT 646_ TSRKD 651_ VLQEM 656_ EMLNA 661_ FSTTI 666_ HVPNI 671_ ATGEQ 676_ LLEAL 681_ ELLGN 686_ FKDKE 691_ RTTIA 696_ QQVKG 701_ KKVWI 706_ GIKKL 711_ LMLIE 716_ MSLQM 721_ DPEYR 726_ VRKFL 731_ ALLRE 736_EGASP
1: Required for vesicle-mediated transport. Catalyzes the fusion of transport vesicles within the Golgi cisternae. Is also required for transport from the endoplasmic reticulum to the Golgi stack. Seems to function as a fusion protein required for the delivery of cargo proteins to all compartments of the Golgi stack independent of vesicle origin. Interaction with AMPAR subunit GRIA2 leads to influence GRIA2 membrane cycling (By similarity)