F-actin-capping protein subunit alpha-2 (CapZ alpha-2)
1_MADLE 6_ EQLSD 11_ EEKVR 16_ IAAKF 21_ IIHAP 26_ PGEFN 31_ EVFND 36_ VRLLL 41_ NNDNL 46_ LREGA 51_ AHAFA 56_ QYNLD 61_ QFTPV 66_ KIEGY 71_ EDQVL 76_ ITEHG 81_ DLGNG 86_ KFLDP 91_ KNRIC 96_ FKFDH 101_ LRKEA 106_ TDPRP 111_ CEVEN 116_ AVESW 121_ RTSVE 126_ TALRA 131_ YVKEH 136_ YPNGV 141_ CTVYG 146_ KKIDG 151_ QQTII 156_ ACIES 161_ HQFQA 166_ KNFWN 171_ GRWRS 176_ EWKFT 181_ ITPST 186_ TQVVG 191_ ILKIQ 196_ VHYYE 201_ DGNVQ 206_ LVSHK 211_ DIQDS 216_ LTVSN 221_ EVQTA 226_ KEFIK 231_ IVEAA 236_ ENEYQ 241_ TAISE 246_ NYQTM 251_ SDTTF 256_ KALRR 261_ QLPVT 266_ RTKID 271_ WNKIL 276_ SYKIG 281_KEMQN
1: F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments