P2Y purinoceptor 1 (P2Y1) (ADP receptor) (Purinergic receptor)
1_MTEVL 6_ WPAVP 11_ NGTDA 16_ AFLAG 21_ PGSSW 26_ GNSTV 31_ ASTAA 36_ VSSSF 41_ KCALT 46_ KTGFQ 51_ FYYLP 56_ AVYIL 61_ VFIIG 66_ FLGNS 71_ VAIWM 76_ FVFHM 81_ KPWSG 86_ ISVYM 91_ FNLAL 96_ ADFLY 101_ VLTLP 106_ ALIFY 111_ YFNKT 116_ DWIFG 121_ DAMCK 126_ LQRFI 131_ FHVNL 136_ YGSIL 141_ FLTCI 146_ SAHRY 151_ SGVVY 156_ PLKSL 161_ GRLKK 166_ KNAIC 171_ ISVLV 176_ WLIVV 181_ VAISP 186_ ILFYS 191_ GTGVR 196_ KNKTI 201_ TCYDT 206_ TSDEY 211_ LRSYF 216_ IYSMC 221_ TTVAM 226_ FCVPL 231_ VLILG 236_ CYGLI 241_ VRALI 246_ YKDLD 251_ NSPLR 256_ RKSIY 261_ LVIIV 266_ LTVFA 271_ VSYIP 276_ FHVMK 281_ TMNLR 286_ ARLDF 291_ QTPAM 296_ CAFND 301_ RVYAT 306_ YQVTR 311_ GLASL 316_ NSCVD 321_ PILYF 326_ LAGDT 331_ FRRRL 336_ SRATR 341_ KASRR 346_ SEANL 351_ QSKSE 356_ DMTLN 361_ ILPEF 366_KQNGD
1: Receptor for extracellular adenine nucleotides such as ADP (PubMed:25822790, PubMed:9038354, PubMed:9442040). In platelets, binding to ADP leads to mobilization of intracellular calcium ions via activation of phospholipase C, a change in platelet shape, and ultimately platelet aggregation (PubMed:9442040)