DNA-binding protein inhibitor ID-4 (Class B basic helix-loop-helix protein 27) (bHLHb27) (Inhibitor of DNA binding 4) (Inhibitor of differentiation 4)
1_MKAVS 6_ PVRPS 11_ GRKAP 16_ SGCGG 21_ GELAL 26_ RCLAE 31_ HGHSL 36_ GGSAA 41_ AAAAA 46_ AAARC 51_ KAAEA 56_ AADEP 61_ ALCLQ 66_ CDMND 71_ CYSRL 76_ RRLVP 81_ TIPPN 86_ KKVSK 91_ VEILQ 96_ HVIDY 101_ ILDLQ 106_ LALET 111_ HPALL 116_ RQPPP 121_ PAPPH 126_ HPAGT 131_ CPAAP 136_ PRTPL 141_ TALNT 146_ DPAGA 151_ VNKQG 156_DSILC
1: Transcriptional regulator (lacking a basic DNA binding domain) which negatively regulates the basic helix-loop-helix (bHLH) transcription factors by forming heterodimers and inhibiting their DNA binding and transcriptional activity. Implicated in regulating a variety of cellular processes, including cellular growth, senescence, differentiation, apoptosis, angiogenesis, and neoplastic transformation (By similarity)