Potassium voltage-gated channel subfamily C member 1 (NGK2) (Voltage-gated potassium channel subunit Kv3.1) (Voltage-gated potassium channel subunit Kv4)
1_MGQGD 6_ ESERI 11_ VINVG 16_ GTRHQ 21_ TYRST 26_ LRTLP 31_ GTRLA 36_ WLAEP 41_ DAHSH 46_ FDYDP 51_ RADEF 56_ FFDRH 61_ PGVFA 66_ HILNY 71_ YRTGK 76_ LHCPA 81_ DVCGP 86_ LYEEE 91_ LAFWG 96_ IDETD 101_ VEPCC 106_ WMTYR 111_ QHRDA 116_ EEALD 121_ SFGGA 126_ PLDNS 131_ ADDAD 136_ ADGPG 141_ DSGDG 146_ EDELE 151_ MTKRL 156_ ALSDS 161_ PDGRP 166_ GGFWR 171_ RWQPR 176_ IWALF 181_ EDPYS 186_ SRYAR 191_ YVAFA 196_ SLFFI 201_ LVSIT 206_ TFCLE 211_ THERF 216_ NPIVN 221_ KTEIE 226_ NVRNG 231_ TQVRY 236_ YREAE 241_ TEAFL 246_ TYIEG 251_ VCVVW 256_ FTFEF 261_ LMRVI 266_ FCPNK 271_ VEFIK 276_ NSLNI 281_ IDFVA 286_ ILPFY 291_ LEVGL 296_ SGLSS 301_ KAAKD 306_ VLGFL 311_ RVVRF 316_ VRILR 321_ IFKLT 326_ RHFVG 331_ LRVLG 336_ HTLRA 341_ STNEF 346_ LLLII 351_ FLALG 356_ VLIFA 361_ TMIYY 366_ AERIG 371_ AQPND 376_ PSASE 381_ HTHFK 386_ NIPIG 391_ FWWAV 396_ VTMTT 401_ LGYGD 406_ MYPQT 411_ WSGML 416_ VGALC 421_ ALAGV 426_ LTIAM 431_ PVPVI 436_ VNNFG 441_ MYYSL 446_ AMAKQ 451_ KLPKK 456_ KKKHI 461_ PRPPQ 466_ LGSPN 471_ YCKSV 476_ VNSPH 481_ HSTQS 486_ DTCPL 491_ AQEEI 496_ LEINR 501_ AGRKP 506_LRGMS
1: Voltage-gated potassium channel that opens in response to the voltage difference across the membrane and through which potassium ions pass in accordance with their electrochemical gradient (PubMed:25401298, PubMed:35840580). The mechanism is time-dependent and inactivation is slow (By similarity). Plays an important role in the rapid repolarization of fast-firing brain neurons (By similarity). Can form functional homotetrameric channels and heterotetrameric channels that contain variable proportions of KCNC2, and possibly other family members as well (By similarity). Contributes to fire sustained trains of very brief action potentials at high frequency in pallidal neurons (By similarity)