26S proteasome non-ATPase regulatory subunit 8 (26S proteasome regulatory subunit RPN12) (26S proteasome regulatory subunit S14) (p31)
1_MFIKG 6_ RAPRA 11_ PPRER 16_ RRATR 21_ GGLRQ 26_ VVAPP 31_ RALGS 36_ TSRPH 41_ FRRAS 46_ VCRRR 51_ CRKSG 56_ GLLAA 61_ SRKMA 66_ AAAVN 71_ GAAGF 76_ SSSGP 81_ AATSG 86_ AVLQA 91_ ATGMY 96_ EQLKG 101_ EWNRK 106_ SPNLS 111_ KCGEE 116_ LGRLK 121_ LVLLE 126_ LNFLP 131_ TTGTK 136_ LTKQQ 141_ LILAR 146_ DILEI 151_ GAQWS 156_ ILRKD 161_ IPSFE 166_ RYMAQ 171_ LKCYY 176_ FDYKE 181_ QLPES 186_ AYMHQ 191_ LLGLN 196_ LLFLL 201_ SQNRV 206_ AEFHT 211_ ELERL 216_ PAKDI 221_ QTNVY 226_ IKHPV 231_ SLEQY 236_ LMEGS 241_ YNKVF 246_ LAKGN 251_ IPAES 256_ YTFFI 261_ DILLD 266_ TIRDE 271_ IAGCI 276_ EKAYE 281_ KILFT 286_ EATRI 291_ LFFNT 296_ PKKMT 301_ DYAKK 306_ RGWVL 311_ GPNNY 316_ YSFAS 321_ QQQKP 326_ EDTTI 331_ PSTEL 336_ AKQVI 341_EYARQ
1: Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair