Hydroxycarboxylic acid receptor 3 (G-protein coupled receptor 109B) (G-protein coupled receptor HM74) (G-protein coupled receptor HM74B) (Niacin receptor 2) (Nicotinic acid receptor 2)
1_MNRHH 6_ LQDHF 11_ LEIDK 16_ KNCCV 21_ FRDDF 26_ IAKVL 31_ PPVLG 36_ LEFIF 41_ GLLGN 46_ GLALW 51_ IFCFH 56_ LKSWK 61_ SSRIF 66_ LFNLA 71_ VADFL 76_ LIICL 81_ PFVMD 86_ YYVRR 91_ SDWKF 96_ GDIPC 101_ RLVLF 106_ MFAMN 111_ RQGSI 116_ IFLTV 121_ VAVDR 126_ YFRVV 131_ HPHHA 136_ LNKIS 141_ NWTAA 146_ IISCL 151_ LWGIT 156_ VGLTV 161_ HLLKK 166_ KLLIQ 171_ NGTAN 176_ VCISF 181_ SICHT 186_ FRWHE 191_ AMFLL 196_ EFFLP 201_ LGIIL 206_ FCSAR 211_ IIWSL 216_ RQRQM 221_ DRHAK 226_ IKRAI 231_ TFIMV 236_ VAIVF 241_ VICFL 246_ PSVVV 251_ RIHIF 256_ WLLHT 261_ SGTQN 266_ CEVYR 271_ SVDLA 276_ FFITL 281_ SFTYM 286_ NSMLD 291_ PVVYY 296_ FSSPS 301_ FPNFF 306_ STLIN 311_ RCLQR 316_ KITGE 321_ PDNNR 326_ STSVE 331_ LTGDP 336_ NKTRG 341_ APEAL 346_ IANSG 351_ EPWSP 356_ SYLGP 361_ TSNNH 366_ SKKGH 371_ CHQEP 376_ ASLEK 381_QLGCC
1: Receptor for 3-OH-octanoid acid mediates a negative feedback regulation of adipocyte lipolysis to counteract prolipolytic influences under conditions of physiological or pathological increases in beta-oxidation rates. Acts as a low affinity receptor for nicotinic acid. This pharmacological effect requires nicotinic acid doses that are much higher than those provided by a normal diet