4-trimethylaminobutyraldehyde dehydrogenase (TMABA-DH) (TMABALDH) (EC 1.2.1.47) (Aldehyde dehydrogenase E3 isozyme) (Aldehyde dehydrogenase family 9 member A1) (EC 1.2.1.3) (Gamma-aminobutyraldehyde dehydrogenase) (EC 1.2.1.19) (R-aminobutyraldehyde dehydrogenase) [Cleaved into: 4-trimethylaminobutyraldehyde dehydrogenase, N-terminally processed]
1_MSTGT 6_ FVVSQ 11_ PLNYR 16_ GGARV 21_ EPADA 26_ SGTEK 31_ AFEPA 36_ TGRVI 41_ ATFTC 46_ SGEKE 51_ VNLAV 56_ QNAKA 61_ AFKIW 66_ SQKSG 71_ MERCR 76_ ILLEA 81_ ARIIR 86_ EREDE 91_ IATME 96_ CINNG 101_ KSIFE 106_ ARLDI 111_ DISWQ 116_ CLEYY 121_ AGLAA 126_ SMAGE 131_ HIQLP 136_ GGSFG 141_ YTRRE 146_ PLGVC 151_ VGIGA 156_ WNYPF 161_ QIASW 166_ KSAPA 171_ LACGN 176_ AMVFK 181_ PSPFT 186_ PVSAL 191_ LLAEI 196_ YSEAG 201_ VPPGL 206_ FNVVQ 211_ GGAAT 216_ GQFLC 221_ QHPDV 226_ AKVSF 231_ TGSVP 236_ TGMKI 241_ MEMSA 246_ KGIKP 251_ VTLEL 256_ GGKSP 261_ LIIFS 266_ DCDMN 271_ NAVKG 276_ ALMAN 281_ FLTQG 286_ QVCCN 291_ GTRVF 296_ VQKEI 301_ LDKFT 306_ EEVVK 311_ QTQRI 316_ KIGDP 321_ LLEDT 326_ RMGPL 331_ INRPH 336_ LERVL 341_ GFVKV 346_ AKEQG 351_ AKVLC 356_ GGDIY 361_ VPEDP 366_ KLKDG 371_ YYMRP 376_ CVLTN 381_ CRDDM 386_ TCVKE 391_ EIFGP 396_ VMSIL 401_ SFDTE 406_ AEVLE 411_ RANDT 416_ TFGLA 421_ AGVFT 426_ RDIQR 431_ AHRVV 436_ AELQA 441_ GTCFI 446_ NNYNV 451_ SPVEL 456_ PFGGY 461_ KKSGF 466_ GRENG 471_ RVTIE 476_ YYSQL 481_ KTVCV 486_EMGDV
1: Converts gamma-trimethylaminobutyraldehyde into gamma-butyrobetaine with high efficiency (in vitro). Can catalyze the irreversible oxidation of a broad range of aldehydes to the corresponding acids in an NAD-dependent reaction, but with low efficiency. Catalyzes the oxidation of aldehydes arising from biogenic amines and polyamines