Transmembrane ascorbate-dependent reductase CYB561 (EC 7.2.1.-) (Cytochrome b-561) (Cytochrome b561)
1_MEGGA 6_ AAATP 11_ TALPY 16_ YVAFS 21_ QLLGL 26_ TLVAM 31_ TGAWL 36_ GLYRG 41_ GIAWE 46_ SDLQF 51_ NAHPL 56_ CMVIG 61_ LIFLQ 66_ GNALL 71_ VYRVF 76_ RNEAK 81_ RTTKV 86_ LHGLL 91_ HIFAL 96_ VIALV 101_ GLVAV 106_ FDYHR 111_ KKGYA 116_ DLYSL 121_ HSWCG 126_ ILVFV 131_ LYFVQ 136_ WLVGF 141_ SFFLF 146_ PGASF 151_ SLRSR 156_ YRPQH 161_ IFFGA 166_ TIFLL 171_ SVGTA 176_ LLGLK 181_ EALLF 186_ NLGGK 191_ YSAFE 196_ PEGVL 201_ ANVLG 206_ LLLAC 211_ FGGAV 216_ LYILT 221_ RADWK 226_ RPSQA 231_ EEQAL 236_ SMDFK 241_ TLTEG 246_DSPGS
1: Transmembrane reductase that uses ascorbate as an electron donor in the cytoplasm and transfers electrons across membranes to reduce monodehydro-L-ascorbate radical in the lumen of secretory vesicles. It is therefore involved the regeneration and homeostasis within secretory vesicles of ascorbate which in turn provides reducing equivalents needed to support the activity of intravesicular enzymes