Centromere protein F (CENP-F) (AH antigen) (Kinetochore protein CENPF) (Mitosin)
1_MSWAL 6_ EEWKE 11_ GLPTR 16_ ALQKI 21_ QELEG 26_ QLDKL 31_ KKEKQ 36_ QRQFQ 41_ LDSLE 46_ AALQK 51_ QKQKV 56_ ENEKT 61_ EGTNL 66_ KRENQ 71_ RLMEI 76_ CESLE 81_ KTKQK 86_ ISHEL 91_ QVKES 96_ QVNFQ 101_ EGQLN 106_ SGKKQ 111_ IEKLE 116_ QELKR 121_ CKSEL 126_ ERSQQ 131_ AAQSA 136_ DVSLN 141_ PCNTP 146_ QKIFT 151_ TPLTP 156_ SQYYS 161_ GSKYE 166_ DLKEK 171_ YNKEV 176_ EERKR 181_ LEAEV 186_ KALQA 191_ KKASQ 196_ TLPQA 201_ TMNHR 206_ DIARH 211_ QASSS 216_ VFSWQ 221_ QEKTP 226_ SHLSS 231_ NSQRT 236_ PIRRD 241_ FSASY 246_ FSGEQ 251_ EVTPS 256_ RSTLQ 261_ IGKRD 266_ ANSSF 271_ FDNSS 276_ SPHLL 281_ DQLKA 286_ QNQEL 291_ RNKIN 296_ ELELR 301_ LQGHE 306_ KEMKG 311_ QVNKF 316_ QELQL 321_ QLEKA 326_ KVELI 331_ EKEKV 336_ LNKCR 341_ DELVR 346_ TTAQY 351_ DQAST 356_ KYTAL 361_ EQKLK 366_ KLTED 371_ LSCQR 376_ QNAES 381_ ARCSL 386_ EQKIK 391_ EKEKE 396_ FQEEL 401_ SRQQR 406_ SFQTL 411_ DQECI 416_ QMKAR 421_ LTQEL 426_ QQAKN 431_ MHNVL 436_ QAELD 441_ KLTSV 446_ KQQLE 451_ NNLEE 456_ FKQKL 461_ CRAEQ 466_ AFQAS 471_ QIKEN 476_ ELRRS 481_ MEEMK 486_ KENNL 491_ LKSHS 496_ EQKAR 501_ EVCHL 506_ EAELK 511_ NIKQC 516_ LNQSQ 521_ NFAEE 526_ MKAKN 531_ TSQET 536_ MLRDL 541_ QEKIN 546_ QQENS 551_ LTLEK 556_ LKLAV 561_ ADLEK 566_ QRDCS 571_ QDLLK 576_ KREHH 581_ IEQLN 586_ DKLSK 591_ TEKES 596_ KALLS 601_ ALELK 606_ KKEYE 611_ ELKEE 616_ KTLFS 621_ CWKSE 626_ NEKLL 631_ TQMES 636_ EKENL 641_ QSKIN 646_ HLETC 651_ LKTQQ 656_ IKSHE 661_ YNERV 666_ RTLEM 671_ DRENL 676_ SVEIR 681_ NLHNV 686_ LDSKS 691_ VEVET 696_ QKLAY 701_ MELQQ 706_ KAEFS 711_ DQKHQ 716_ KEIEN 721_ MCLKT 726_ SQLTG 731_ QVEDL 736_ EHKLQ 741_ LLSNE 746_ IMDKD 751_ RCYQD 756_ LHAEY 761_ ESLRD 766_ LLKSK 771_ DASLV 776_ TNEDH 781_ QRSLL 786_ AFDQQ 791_ PAMHH 796_ SFANI 801_ IGEQG 806_ SMPSE 811_ RSECR 816_ LEADQ 821_ SPKNS 826_ AILQN 831_ RVDSL 836_ EFSLE 841_ SQKQM 846_ NSDLQ 851_ KQCEE 856_ LVQIK 861_ GEIEE 866_ NLMKA 871_ EQMHQ 876_ SFVAE 881_ TSQRI 886_ SKLQE 891_ DTSAH 896_ QNVVA 901_ ETLSA 906_ LENKE 911_ KELQL 916_ LNDKV 921_ ETEQA 926_ EIQEL 931_ KKSNH 936_ LLEDS 941_ LKELQ 946_ LLSET 951_ LSLEK 956_ KEMSS 961_ IISLN 966_ KREIE 971_ ELTQE 976_ NGTLK 981_ EINAS 986_ LNQEK 991_ MNLIQ 996_ KSESF 1001_ ANYID 1006_ EREKS 1011_ ISELS 1016_ DQYKQ 1021_ EKLIL 1026_ LQRCE 1031_ ETGNA 1036_ YEDLS 1041_ QKYKA 1046_ AQEKN 1051_ SKLEC 1056_ LLNEC 1061_ TSLCE 1066_ NRKNE 1071_ LEQLK 1076_ EAFAK 1081_ EHQEF 1086_ LTKLA 1091_ FAEER 1096_ NQNLM 1101_ LELET 1106_ VQQAL 1111_ RSEMT 1116_ DNQNN 1121_ SKSEA 1126_ GGLKQ 1131_ EIMTL 1136_ KEEQN 1141_ KMQKE 1146_ VNDLL 1151_ QENEQ 1156_ LMKVM 1161_ KTKHE 1166_ CQNLE 1171_ SEPIR 1176_ NSVKE 1181_ RESER 1186_ NQCNF 1191_ KPQMD 1196_ LEVKE 1201_ ISLDS 1206_ YNAQL 1211_ VQLEA 1216_ MLRNK 1221_ ELKLQ 1226_ ESEKE 1231_ KECLQ 1236_ HELQT 1241_ IRGDL 1246_ ETSNL 1251_ QDMQS 1256_ QEISG 1261_ LKDCE 1266_ IDAEE 1271_ KYISG 1276_ PHELS 1281_ TSQND 1286_ NAHLQ 1291_ CSLQT 1296_ TMNKL 1301_ NELEK 1306_ ICEIL 1311_ QAEKY 1316_ ELVTE 1321_ LNDSR 1326_ SECIT 1331_ ATRKM 1336_ AEEVG 1341_ KLLNE 1346_ VKILN 1351_ DDSGL 1356_ LHGEL 1361_ VEDIP 1366_ GGEFG 1371_ EQPNE 1376_ QHPVS 1381_ LAPLD 1386_ ESNSY 1391_ EHLTL 1396_ SDKEV 1401_ QMHFA 1406_ ELQEK 1411_ FLSLQ 1416_ SEHKI 1421_ LHDQH 1426_ CQMSS 1431_ KMSEL 1436_ QTYVD 1441_ SLKAE 1446_ NLVLS 1451_ TNLRN 1456_ FQGDL 1461_ VKEMQ 1466_ LGLEE 1471_ GLVPS 1476_ LSSSC 1481_ VPDSS 1486_ SLSSL 1491_ GDSSF 1496_ YRALL 1501_ EQTGD 1506_ MSLLS 1511_ NLEGA 1516_ VSANQ 1521_ CSVDE 1526_ VFCSS 1531_ LQEEN 1536_ LTRKE 1541_ TPSAP 1546_ AKGVE 1551_ ELESL 1556_ CEVYR 1561_ QSLEK 1566_ LEEKM 1571_ ESQGI 1576_ MKNKE 1581_ IQELE 1586_ QLLSS 1591_ ERQEL 1596_ DCLRK 1601_ QYLSE 1606_ NEQWQ 1611_ QKLTS 1616_ VTLEM 1621_ ESKLA 1626_ AEKKQ 1631_ TEQLS 1636_ LELEV 1641_ ARLQL 1646_ QGLDL 1651_ SSRSL 1656_ LGIDT 1661_ EDAIQ 1666_ GRNES 1671_ CDISK 1676_ EHTSE 1681_ TTERT 1686_ PKHDV 1691_ HQICD 1696_ KDAQQ 1701_ DLNLD 1706_ IEKIT 1711_ ETGAV 1716_ KPTGE 1721_ CSGEQ 1726_ SPDTN 1731_ YEPPG 1736_ EDKTQ 1741_ GSSEC 1746_ ISELS 1751_ FSGPN 1756_ ALVPM 1761_ DFLGN 1766_ QEDIH 1771_ NLQLR 1776_ VKETS 1781_ NENLR 1786_ LLHVI 1791_ EDRDR 1796_ KVESL 1801_ LNEMK 1806_ ELDSK 1811_ LHLQE 1816_ VQLMT 1821_ KIEAC 1826_ IELEK 1831_ IVGEL 1836_ KKENS 1841_ DLSEK 1846_ LEYFS 1851_ CDHQE 1856_ LLQRV 1861_ ETSEG 1866_ LNSDL 1871_ EMHAD 1876_ KSSRE 1881_ DIGDN 1886_ VAKVN 1891_ DSWKE 1896_ RFLDV 1901_ ENELS 1906_ RIRSE 1911_ KASIE 1916_ HEALY 1921_ LEADL 1926_ EVVQT 1931_ EKLCL 1936_ EKDNE 1941_ NKQKV 1946_ IVCLE 1951_ EELSV 1956_ VTSER 1961_ NQLRG 1966_ ELDTM 1971_ SKKTT 1976_ ALDQL 1981_ SEKMK 1986_ EKTQE 1991_ LESHQ 1996_ SECLH 2001_ CIQVA 2006_ EAEVK 2011_ EKTEL 2016_ LQTLS 2021_ SDVSE 2026_ LLKDK 2031_ THLQE 2036_ KLQSL 2041_ EKDSQ 2046_ ALSLT 2051_ KCELE 2056_ NQIAQ 2061_ LNKEK 2066_ ELLVK 2071_ ESESL 2076_ QARLS 2081_ ESDYE 2086_ KLNVS 2091_ KALEA 2096_ ALVEK 2101_ GEFAL 2106_ RLSST 2111_ QEEVH 2116_ QLRRG 2121_ IEKLR 2126_ VRIEA 2131_ DEKKQ 2136_ LHIAE 2141_ KLKER 2146_ EREND 2151_ SLKDK 2156_ VENLE 2161_ RELQM 2166_ SEENQ 2171_ ELVIL 2176_ DAENS 2181_ KAEVE 2186_ TLKTQ 2191_ IEEMA 2196_ RSLKV 2201_ FELDL 2206_ VTLRS 2211_ EKENL 2216_ TKQIQ 2221_ EKQGQ 2226_ LSELD 2231_ KLLSS 2236_ FKSLL 2241_ EEKEQ 2246_ AEIQI 2251_ KEESK 2256_ TAVEM 2261_ LQNQL 2266_ KELNE 2271_ AVAAL 2276_ CGDQE 2281_ IMKAT 2286_ EQSLD 2291_ PPIEE 2296_ EHQLR 2301_ NSIEK 2306_ LRARL 2311_ EADEK 2316_ KQLCV 2321_ LQQLK 2326_ ESEHH 2331_ ADLLK 2336_ GRVEN 2341_ LEREL 2346_ EIART 2351_ NQEHA 2356_ ALEAE 2361_ NSKGE 2366_ VETLK 2371_ AKIEG 2376_ MTQSL 2381_ RGLEL 2386_ DVVTI 2391_ RSEKE 2396_ NLTNE 2401_ LQKEQ 2406_ ERISE 2411_ LEIIN 2416_ SSFEN 2421_ ILQEK 2426_ EQEKV 2431_ QMKEK 2436_ SSTAM 2441_ EMLQT 2446_ QLKEL 2451_ NERVA 2456_ ALHND 2461_ QEACK 2466_ AKEQN 2471_ LSSQV 2476_ ECLEL 2481_ EKAQL 2486_ LQGLD 2491_ EAKNN 2496_ YIVLQ 2501_ SSVNG 2506_ LIQEV 2511_ EDGKQ 2516_ KLEKK 2521_ DEEIS 2526_ RLKNQ 2531_ IQDQE 2536_ QLVSK 2541_ LSQVE 2546_ GEHQL 2551_ WKEQN 2556_ LELRN 2561_ LTVEL 2566_ EQKIQ 2571_ VLQSK 2576_ NASLQ 2581_ DTLEV 2586_ LQSSY 2591_ KNLEN 2596_ ELELT 2601_ KMDKM 2606_ SFVEK 2611_ VNKMT 2616_ AKETE 2621_ LQREM 2626_ HEMAQ 2631_ KTAEL 2636_ QEELS 2641_ GEKNR 2646_ LAGEL 2651_ QLLLE 2656_ EIKSS 2661_ KDQLK 2666_ ELTLE 2671_ NSELK 2676_ KSLDC 2681_ MHKDQ 2686_ VEKEG 2691_ KVREE 2696_ IAEYQ 2701_ LRLHE 2706_ AEKKH 2711_ QALLL 2716_ DTNKQ 2721_ YEVEI 2726_ QTYRE 2731_ KLTSK 2736_ EECLS 2741_ SQKLE 2746_ IDLLK 2751_ SSKEE 2756_ LNNSL 2761_ KATTQ 2766_ ILEEL 2771_ KKTKM 2776_ DNLKY 2781_ VNQLK 2786_ KENER 2791_ AQGKM 2796_ KLLIK 2801_ SCKQL 2806_ EEEKE 2811_ ILQKE 2816_ LSQLQ 2821_ AAQEK 2826_ QKTGT 2831_ VMDTK 2836_ VDELT 2841_ TEIKE 2846_ LKETL 2851_ EEKTK 2856_ EADEY 2861_ LDKYC 2866_ SLLIS 2871_ HEKLE 2876_ KAKEM 2881_ LETQV 2886_ AHLCS 2891_ QQSKQ 2896_ DSRGS 2901_ PLLGP 2906_ VVPGP 2911_ SPIPS 2916_ VTEKR 2921_ LSSGQ 2926_ NKASG 2931_ KRQRS 2936_ SGIWE 2941_ NGRGP 2946_ TPATP 2951_ ESFSK 2956_ KSKKA 2961_ VMSGI 2966_ HPAED 2971_ TEGTE 2976_ FEPEG 2981_ LPEVV 2986_ KKGFA 2991_ DIPTG 2996_ KTSPY 3001_ ILRRT 3006_ TMATR 3011_ TSPRL 3016_ AAQKL 3021_ ALSPL 3026_ SLGKE 3031_ NLAES 3036_ SKPTA 3041_ GGSRS 3046_ QKVKV 3051_ AQRSP 3056_ VDSGT 3061_ ILREP 3066_ TTKSV 3071_ PVNNL 3076_ PERSP 3081_ TDSPR 3086_ EGLRV 3091_ KRGRL 3096_ VPSPK 3101_ AGLES 3106_NGSEN
1: Required for kinetochore function and chromosome segregation in mitosis. Required for kinetochore localization of dynein, LIS1, NDE1 and NDEL1. Regulates recycling of the plasma membrane by acting as a link between recycling vesicles and the microtubule network though its association with STX4 and SNAP25. Acts as a potential inhibitor of pocket protein-mediated cellular processes during development by regulating the activity of RB proteins during cell division and proliferation. May play a regulatory or permissive role in the normal embryonic cardiomyocyte cell cycle and in promoting continued mitosis in transformed, abnormally dividing neonatal cardiomyocytes. Interaction with RB directs embryonic stem cells toward a cardiac lineage. Involved in the regulation of DNA synthesis and hence cell cycle progression, via its C-terminus. Has a potential role regulating skeletal myogenesis and in cell differentiation in embryogenesis. Involved in dendritic cell regulation of T-cell immunity against chlamydia