Gene name: TTPA

Uniprot entry:

P49638

Protein names:

Alpha-tocopherol transfer protein (Alpha-TTP)

Protein sequence:

1_MAEAR 6_ SQPSA 11_ GPQLN 16_ ALPDH 21_ SPLLQ 26_ PGLAA 31_ LRRRA 36_ REAGV 41_ PLAPL 46_ PLTDS 51_ FLLRF 56_ LRARD 61_ FDLDL 66_ AWRLL 71_ KNYYK 76_ WRAEC 81_ PEISA 86_ DLHPR 91_ SIIGL 96_ LKAGY 101_ HGVLR 106_ SRDPT 111_ GSKVL 116_ IYRIA 121_ HWDPK 126_ VFTAY 131_ DVFRV 136_ SLITS 141_ ELIVQ 146_ EVETQ 151_ RNGIK 156_ AIFDL 161_ EGWQF 166_ SHAFQ 171_ ITPSV 176_ AKKIA 181_ AVLTD 186_ SFPLK 191_ VRGIH 196_ LINEP 201_ VIFHA 206_ VFSMI 211_ KPFLT 216_ EKIKE 221_ RIHMH 226_ GNNYK 231_ QSLLQ 236_ HFPDI 241_ LPLEY 246_ GGEEF 251_ SMEDI 256_ CQEWT 261_ NFIMK 266_ SEDYL 271_SSISE

Protein annotations

Protein functions:

1: Binds alpha-tocopherol, enhances its transfer between separate membranes, and stimulates its release from liver cells (PubMed:7887897). Binds both phosphatidylinositol 3,4-bisphosphate and phosphatidylinositol 4,5-bisphosphate; the resulting conformation change is important for the release of the bound alpha-tocopherol (By similarity)