Homeobox protein Hox-A1 (Homeobox protein Hox-1F)
1_MDNAR 6_ MNSFL 11_ EYPIL 16_ SSGDS 21_ GTCSA 26_ RAYPS 31_ DHRIT 36_ TFQSC 41_ AVSAN 46_ SCGGD 51_ DRFLV 56_ GRGVQ 61_ IGSPH 66_ HHHHH 71_ HHHHP 76_ QPATY 81_ QTSGN 86_ LGVSY 91_ SHSSC 96_ GPSYG 101_ SQNFS 106_ APYSP 111_ YALNQ 116_ EADVS 121_ GGYPQ 126_ CAPAV 131_ YSGNL 136_ SSPMV 141_ QHHHH 146_ HQGYA 151_ GGAVG 156_ SPQYI 161_ HHSYG 166_ QEHQS 171_ LALAT 176_ YNNSL 181_ SPLHA 186_ SHQEA 191_ CRSPA 196_ SETSS 201_ PAQTF 206_ DWMKV 211_ KRNPP 216_ KTGKV 221_ GEYGY 226_ LGQPN 231_ AVRTN 236_ FTTKQ 241_ LTELE 246_ KEFHF 251_ NKYLT 256_ RARRV 261_ EIAAS 266_ LQLNE 271_ TQVKI 276_ WFQNR 281_ RMKQK 286_ KREKE 291_ GLLPI 296_ SPATP 301_ PGNDE 306_ KAEES 311_ SEKSS 316_ SSPCV 321_ PSPGS 326_STSDT
1: Sequence-specific transcription factor (By similarity). Regulates multiple developmental processes including brainstem, inner and outer ear, abducens nerve and cardiovascular development and morphogenesis as well as cognition and behavior (PubMed:16155570). Also part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Acts on the anterior body structures. Seems to act in the maintenance and/or generation of hindbrain segments (By similarity). Activates transcription in the presence of PBX1A and PKNOX1 (By similarity)