CCAAT/enhancer-binding protein delta (C/EBP delta) (Nuclear factor NF-IL6-beta) (NF-IL6-beta)
1_MSAAL 6_ FSLDG 11_ PARGA 16_ PWPAE 21_ PAPFY 26_ EPGRA 31_ GKPGR 36_ GAEPG 41_ ALGEP 46_ GAAAP 51_ AMYDD 56_ ESAID 61_ FSAYI 66_ DSMAA 71_ VPTLE 76_ LCHDE 81_ LFADL 86_ FNSNH 91_ KAGGA 96_ GPLEL 101_ LPGGP 106_ ARPLG 111_ PGPAA 116_ PRLLK 121_ REPDW 126_ GDGDA 131_ PGSLL 136_ PAQVA 141_ ACAQT 146_ VVSLA 151_ AAGQP 156_ TPPTS 161_ PEPPR 166_ SSPRQ 171_ TPAPG 176_ PAREK 181_ SAGKR 186_ GPDRG 191_ SPEYR 196_ QRRER 201_ NNIAV 206_ RKSRD 211_ KAKRR 216_ NQEMQ 221_ QKLVE 226_ LSAEN 231_ EKLHQ 236_ RVEQL 241_ TRDLA 246_ GLRQF 251_ FKQLP 256_ SPPFL 261_PAAGT
1: Transcription activator that recognizes two different DNA motifs: the CCAAT homology common to many promoters and the enhanced core homology common to many enhancers (PubMed:16397300). Important transcription factor regulating the expression of genes involved in immune and inflammatory responses (PubMed:16397300, PubMed:1741402). Transcriptional activator that enhances IL6 transcription alone and as heterodimer with CEBPB (PubMed:1741402)