Acyl-coenzyme A thioesterase 2, mitochondrial (Acyl-CoA thioesterase 2) (EC 3.1.2.2) (Acyl-coenzyme A thioester hydrolase 2a) (CTE-Ia) (Long-chain acyl-CoA thioesterase 2) (ZAP128)
1_MSNKL 6_ LSPHP 11_ HSVVL 16_ RSEFK 21_ MASSP 26_ AVLRA 31_ SRLYQ 36_ WSLKS 41_ SAQFL 46_ GSPQL 51_ RQVGQ 56_ IIRVP 61_ ARMAA 66_ TLILE 71_ PAGRC 76_ CWDEP 81_ VRIAV 86_ RGLAP 91_ EQPVT 96_ LRASL 101_ RDEKG 106_ ALFQA 111_ HARYR 116_ ADTLG 121_ ELDLE 126_ RAPAL 131_ GGSFA 136_ GLEPM 141_ GLLWA 146_ LEPEK 151_ PLVRL 156_ VKRDV 161_ RTPLA 166_ VELEV 171_ LDGHD 176_ PDPGR 181_ LLCQT 186_ RHERY 191_ FLPPG 196_ VRREP 201_ VRVGR 206_ VRGTL 211_ FLPPE 216_ PGPFP 221_ GIVDM 226_ FGTGG 231_ GLLEY 236_ RASLL 241_ AGKGF 246_ AVMAL 251_ AYYNY 256_ EDLPK 261_ TMETL 266_ HLEYF 271_ EEAMN 276_ YLLSH 281_ PEVKG 286_ PGVGL 291_ LGISK 296_ GGELC 301_ LSMAS 306_ FLKGI 311_ TAAVV 316_ INGSV 321_ ANVGG 326_ TLHYK 331_ GETLP 336_ PVGVN 341_ RNRIK 346_ VTKDG 351_ YADIV 356_ DVLNS 361_ PLEGP 366_ DQKSF 371_ IPVER 376_ AESTF 381_ LFLVG 386_ QDDHN 391_ WKSEF 396_ YANEA 401_ CKRLQ 406_ AHGRR 411_ KPQII 416_ CYPET 421_ GHYIE 426_ PPYFP 431_ LCRAS 436_ LHALV 441_ GSPII 446_ WGGEP 451_ RAHAM 456_ AQVDA 461_ WKQLQ 466_ TFFHK 471_ HLGGH 476_EGTIP
1: Catalyzes the hydrolysis of acyl-CoAs into free fatty acids and coenzyme A (CoASH), regulating their respective intracellular levels (PubMed:10944470, PubMed:16940157). Displays higher activity toward long chain acyl CoAs (C14-C20) (PubMed:10944470, PubMed:16940157). The enzyme is involved in enhancing the hepatic fatty acid oxidation in mitochondria (By similarity)