Placenta growth factor (PlGF)
1_MPVMR 6_ LFPCF 11_ LQLLA 16_ GLALP 21_ AVPPQ 26_ QWALS 31_ AGNGS 36_ SEVEV 41_ VPFQE 46_ VWGRS 51_ YCRAL 56_ ERLVD 61_ VVSEY 66_ PSEVE 71_ HMFSP 76_ SCVSL 81_ LRCTG 86_ CCGDE 91_ NLHCV 96_ PVETA 101_ NVTMQ 106_ LLKIR 111_ SGDRP 116_ SYVEL 121_ TFSQH 126_ VRCEC 131_ RHSPG 136_ RQSPD 141_ MPGDF 146_ RADAP 151_ SFLPP 156_ RRSLP 161_ MLFRM 166_ EWGCA 171_ LTGSQ 176_ SAVWP 181_ SSPVP 186_ EEIPR 191_ MHPGR 196_ NGKKQ 201_ QRKPL 206_ REKMK 211_ PERCG 216_DAVPR
1: Growth factor active in angiogenesis and endothelial cell growth, stimulating their proliferation and migration. It binds to the receptor FLT1/VEGFR-1. Isoform PlGF-2 binds NRP1/neuropilin-1 and NRP2/neuropilin-2 in a heparin-dependent manner. Also promotes cell tumor growth