Vascular endothelial growth factor C (VEGF-C) (Flt4 ligand) (Flt4-L) (Vascular endothelial growth factor-related protein) (VRP)
1_MHLLG 6_ FFSVA 11_ CSLLA 16_ AALLP 21_ GPREA 26_ PAAAA 31_ AFESG 36_ LDLSD 41_ AEPDA 46_ GEATA 51_ YASKD 56_ LEEQL 61_ RSVSS 66_ VDELM 71_ TVLYP 76_ EYWKM 81_ YKCQL 86_ RKGGW 91_ QHNRE 96_ QANLN 101_ SRTEE 106_ TIKFA 111_ AAHYN 116_ TEILK 121_ SIDNE 126_ WRKTQ 131_ CMPRE 136_ VCIDV 141_ GKEFG 146_ VATNT 151_ FFKPP 156_ CVSVY 161_ RCGGC 166_ CNSEG 171_ LQCMN 176_ TSTSY 181_ LSKTL 186_ FEITV 191_ PLSQG 196_ PKPVT 201_ ISFAN 206_ HTSCR 211_ CMSKL 216_ DVYRQ 221_ VHSII 226_ RRSLP 231_ ATLPQ 236_ CQAAN 241_ KTCPT 246_ NYMWN 251_ NHICR 256_ CLAQE 261_ DFMFS 266_ SDAGD 271_ DSTDG 276_ FHDIC 281_ GPNKE 286_ LDEET 291_ CQCVC 296_ RAGLR 301_ PASCG 306_ PHKEL 311_ DRNSC 316_ QCVCK 321_ NKLFP 326_ SQCGA 331_ NREFD 336_ ENTCQ 341_ CVCKR 346_ TCPRN 351_ QPLNP 356_ GKCAC 361_ ECTES 366_ PQKCL 371_ LKGKK 376_ FHHQT 381_ CSCYR 386_ RPCTN 391_ RQKAC 396_ EPGFS 401_ YSEEV 406_ CRCVP 411_SYWKR
1: Growth factor active in angiogenesis, and endothelial cell growth, stimulating their proliferation and migration and also has effects on the permeability of blood vessels. May function in angiogenesis of the venous and lymphatic vascular systems during embryogenesis, and also in the maintenance of differentiated lymphatic endothelium in adults. Binds and activates KDR/VEGFR2 and FLT4/VEGFR3 receptors