Nuclear pore complex protein Nup153 (153 kDa nucleoporin) (Nucleoporin Nup153)
1_MASGA 6_ GGVGG 11_ GGGGK 16_ IRTRR 21_ CHQGP 26_ IKPYQ 31_ QGRQQ 36_ HQGIL 41_ SRVTE 46_ SVKNI 51_ VPGWL 56_ QRYFN 61_ KNEDV 66_ CSCST 71_ DTSEV 76_ PRWPE 81_ NKEDH 86_ LVYAD 91_ EESSN 96_ ITDGR 101_ ITPEP 106_ AVSNT 111_ EEPST 116_ TSTAS 121_ NYPDV 126_ LTRPS 131_ LHRSH 136_ LNFSM 141_ LESPA 146_ LHCQP 151_ STSSA 156_ FPIGS 161_ SGFSL 166_ VKEIK 171_ DSTSQ 176_ HDDDN 181_ ISTTS 186_ GFSSR 191_ ASDKD 196_ ITVSK 201_ NTSLP 206_ PLWSP 211_ EAERS 216_ HSLSQ 221_ HTATS 226_ SKKPA 231_ FNLSA 236_ FGTLS 241_ PSLGN 246_ SSILK 251_ TSQLG 256_ DSPFY 261_ PGKTT 266_ YGGAA 271_ AAVRQ 276_ SKLRN 281_ TPYQA 286_ PVRRQ 291_ MKAKQ 296_ LSAQS 301_ YGVTS 306_ STARR 311_ ILQSL 316_ EKMSS 321_ PLADA 326_ KRIPS 331_ IVSSP 336_ LNSPL 341_ DRSGI 346_ DITDF 351_ QAKRE 356_ KVDSQ 361_ YPPVQ 366_ RLMTP 371_ KPVSI 376_ ATNRS 381_ VYFKP 386_ SLTPS 391_ GEFRK 396_ TNQRI 401_ DNKCS 406_ TGYEK 411_ NMTPG 416_ QNREQ 421_ RESGF 426_ SYPNF 431_ SLPAA 436_ NGLSS 441_ GVGGG 446_ GGKMR 451_ RERTR 456_ FVASK 461_ PLEEE 466_ EMEVP 471_ VLPKI 476_ SLPIT 481_ SSSLP 486_ TFNFS 491_ SPEIT 496_ TSSPS 501_ PINSS 506_ QALTN 511_ KVQMT 516_ SPSST 521_ GSPMF 526_ KFSSP 531_ IVKST 536_ EANVL 541_ PPSSI 546_ GFTFS 551_ VPVAK 556_ TAELS 561_ GSSST 566_ LEPII 571_ SSSAH 576_ HVTTV 581_ NSTNC 586_ KKTPP 591_ EDCEG 596_ PFRPA 601_ EILKE 606_ GSVLD 611_ ILKSP 616_ GFASP 621_ KIDSV 626_ AAQPT 631_ ATSPV 636_ VYTRP 641_ AISSF 646_ SSSGI 651_ GFGES 656_ LKAGS 661_ SWQCD 666_ TCLLQ 671_ NKVTD 676_ NKCIA 681_ CQAAK 686_ LSPRD 691_ TAKQT 696_ GIETP 701_ NKSGK 706_ TTLSA 711_ SGTGF 716_ GDKFK 721_ PVIGT 726_ WDCDT 731_ CLVQN 736_ KPEAI 741_ KCVAC 746_ ETPKP 751_ GTCVK 756_ RALTL 761_ TVVSE 766_ SAETM 771_ TASSS 776_ SCTVT 781_ TGTLG 786_ FGDKF 791_ KRPIG 796_ SWECS 801_ VCCVS 806_ NNAED 811_ NKCVS 816_ CMSEK 821_ PGSSV 826_ PASSS 831_ STVPV 836_ SLPSG 841_ GSLGL 846_ EKFKK 851_ PEGSW 856_ DCELC 861_ LVQNK 866_ ADSTK 871_ CLACE 876_ SAKPG 881_ TKSGF 886_ KGFDT 891_ SSSSS 896_ NSAAS 901_ SSFKF 906_ GVSSS 911_ SSGPS 916_ QTLTS 921_ TGNFK 926_ FGDQG 931_ GFKIG 936_ VSSDS 941_ GSINP 946_ MSEGF 951_ KFSKP 956_ IGDFK 961_ FGVSS 966_ ESKPE 971_ EVKKD 976_ SKNDN 981_ FKFGL 986_ SSGLS 991_ NPVSL 996_ TPFQF 1001_ GVSNL 1006_ GQEEK 1011_ KEELP 1016_ KSSSA 1021_ GFSFG 1026_ TGVIN 1031_ STPAP 1036_ ANTIV 1041_ TSENK 1046_ SSFNL 1051_ GTIET 1056_ KSASV 1061_ APFTC 1066_ KTSEA 1071_ KKEEM 1076_ PATKG 1081_ GFSFG 1086_ NVEPA 1091_ SLPSA 1096_ SVFVL 1101_ GRTEE 1106_ KQQEP 1111_ VTSTS 1116_ LVFGK 1121_ KADNE 1126_ EPKCQ 1131_ PVFSF 1136_ GNSEQ 1141_ TKDEN 1146_ SSKST 1151_ FSFSM 1156_ TKPSE 1161_ KESEQ 1166_ PAKAT 1171_ FAFGA 1176_ QTSTT 1181_ ADQGA 1186_ AKPVF 1191_ SFLNN 1196_ SSSSS 1201_ STPAT 1206_ SAGGG 1211_ IFGSS 1216_ TSSSN 1221_ PPVAT 1226_ FVFGQ 1231_ SSNPV 1236_ SSSAF 1241_ GNTAE 1246_ SSTSQ 1251_ SLLFS 1256_ QDSKL 1261_ ATTSS 1266_ TGTAV 1271_ TPFVF 1276_ GPGAS 1281_ SNNTT 1286_ TSGFG 1291_ FGATT 1296_ TSSSA 1301_ GSSFV 1306_ FGTGP 1311_ SAPSA 1316_ SPAFG 1321_ ANQTP 1326_ TFGQS 1331_ QGASQ 1336_ PNPPG 1341_ FGSIS 1346_ SSTAL 1351_ FPTGS 1356_ QPAPP 1361_ TFGTV 1366_ SSSSQ 1371_ PPVFG 1376_ QQPSQ 1381_ SAFGS 1386_ GTTPN 1391_ SSSAF 1396_ QFGSS 1401_ TTNFN 1406_ FTNNS 1411_ PSGVF 1416_ TFGAN 1421_ SSTPA 1426_ ASAQP 1431_ SGSGG 1436_ FPFNQ 1441_ SPAAF 1446_ TVGSN 1451_ GKNVF 1456_ SSSGT 1461_ SFSGR 1466_KIKTA
1: Component of the nuclear pore complex (NPC), a complex required for the trafficking across the nuclear envelope. Functions as a scaffolding element in the nuclear phase of the NPC essential for normal nucleocytoplasmic transport of proteins and mRNAs. Involved in the quality control and retention of unspliced mRNAs in the nucleus; in association with TPR, regulates the nuclear export of unspliced mRNA species bearing constitutive transport element (CTE) in a NXF1- and KHDRBS1-independent manner. Mediates TPR anchoring to the nuclear membrane at NPC. The repeat-containing domain may be involved in anchoring other components of the NPC to the pore membrane. Possible DNA-binding subunit of the nuclear pore complex (NPC)
2: (Microbial infection) Interacts with HIV-1 caspid protein P24 and thereby promotes the integration of the virus in the nucleus of non-dividing cells (in vitro)
3: (Microbial infection) Binds HIV-2 protein vpx and thereby promotes the nuclear translocation of the lentiviral genome (in vitro)