Regulator of G-protein signaling 4 (RGP4) (RGS4)
1_MCKGL 6_ AGLPA 11_ SCLRS 16_ AKDMK 21_ HRLGF 26_ LLQKS 31_ DSCEH 36_ NSSHN 41_ KKDKV 46_ VICQR 51_ VSQEE 56_ VKKWA 61_ ESLEN 66_ LISHE 71_ CGLAA 76_ FKAFL 81_ KSEYS 86_ EENID 91_ FWISC 96_ EEYKK 101_ IKSPS 106_ KLSPK 111_ AKKIY 116_ NEFIS 121_ VQATK 126_ EVNLD 131_ SCTRE 136_ ETSRN 141_ MLEPT 146_ ITCFD 151_ EAQKK 156_ IFNLM 161_ EKDSY 166_ RRFLK 171_ SRFYL 176_ DLVNP 181_ SSCGA 186_ EKQKG 191_ AKSSA 196_DCASL
1: Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. Activity on G(z)-alpha is inhibited by phosphorylation of the G-protein. Activity on G(z)-alpha and G(i)-alpha-1 is inhibited by palmitoylation of the G-protein