Cytosolic purine 5'-nucleotidase (EC 3.1.3.5) (EC 3.1.3.99) (Cytosolic 5'-nucleotidase II) (cN-II) (Cytosolic IMP/GMP-specific 5'-nucleotidase) (Cytosolic nucleoside phosphotransferase 5'N) (EC 2.7.1.77) (High Km 5'-nucleotidase)
1_MSTSW 6_ SDRLQ 11_ NAADM 16_ PANMD 21_ KHALK 26_ KYRRE 31_ AYHRV 36_ FVNRS 41_ LAMEK 46_ IKCFG 51_ FDMDY 56_ TLAVY 61_ KSPEY 66_ ESLGF 71_ ELTVE 76_ RLVSI 81_ GYPQE 86_ LLSFA 91_ YDSTF 96_ PTRGL 101_ VFDTL 106_ YGNLL 111_ KVDAY 116_ GNLLV 121_ CAHGF 126_ NFIRG 131_ PETRE 136_ QYPNK 141_ FIQRD 146_ DTERF 151_ YILNT 156_ LFNLP 161_ ETYLL 166_ ACLVD 171_ FFTNC 176_ PRYTS 181_ CETGF 186_ KDGDL 191_ FMSYR 196_ SMFQD 201_ VRDAV 206_ DWVHY 211_ KGSLK 216_ EKTVE 221_ NLEKY 226_ VVKDG 231_ KLPLL 236_ LSRMK 241_ EVGKV 246_ FLATN 251_ SDYKY 256_ TDKIM 261_ TYLFD 266_ FPHGP 271_ KPGSS 276_ HRPWQ 281_ SYFDL 286_ ILVDA 291_ RKPLF 296_ FGEGT 301_ VLRQV 306_ DTKTG 311_ KLKIG 316_ TYTGP 321_ LQHGI 326_ VYSGG 331_ SSDTI 336_ CDLLG 341_ AKGKD 346_ ILYIG 351_ DHIFG 356_ DILKS 361_ KKRQG 366_ WRTFL 371_ VIPEL 376_ AQELH 381_ VWTDK 386_ SSLFE 391_ ELQSL 396_ DIFLA 401_ ELYKH 406_ LDSSS 411_ NERPD 416_ ISSIQ 421_ RRIKK 426_ VTHDM 431_ DMCYG 436_ MMGSL 441_ FRSGS 446_ RQTLF 451_ ASQVM 456_ RYADL 461_ YAASF 466_ INLLY 471_ YPFSY 476_ LFRAA 481_ HVLMP 486_ HESTV 491_ EHTHV 496_ DINEM 501_ ESPLA 506_ TRNRT 511_ SVDFK 516_ DTDYK 521_ RHQLT 526_ RSISE 531_ IKPPN 536_ LFPLA 541_ PQEIT 546_ HCHDE 551_ DDDEE 556_EEEEE
1: Broad specificity cytosolic 5'-nucleotidase that catalyzes the dephosphorylation of 6-hydroxypurine nucleoside 5'-monophosphates (PubMed:10092873, PubMed:12907246, PubMed:1659319, PubMed:9371705). In addition, possesses a phosphotransferase activity by which it can transfer a phosphate from a donor nucleoside monophosphate to an acceptor nucleoside, preferably inosine, deoxyinosine and guanosine (PubMed:1659319, PubMed:9371705). Has the highest activities for IMP and GMP followed by dIMP, dGMP and XMP (PubMed:10092873, PubMed:12907246, PubMed:1659319, PubMed:9371705). Could also catalyze the transfer of phosphates from pyrimidine monophosphates but with lower efficiency (PubMed:1659319, PubMed:9371705). Through these activities regulates the purine nucleoside/nucleotide pools within the cell (PubMed:10092873, PubMed:12907246, PubMed:1659319, PubMed:9371705)