Type-2 angiotensin II receptor (Angiotensin II type-2 receptor) (AT2)
1_MKGNS 6_ TLATT 11_ SKNIT 16_ SGLHF 21_ GLVNI 26_ SGNNE 31_ STLNC 36_ SQKPS 41_ DKHLD 46_ AIPIL 51_ YYIIF 56_ VIGFL 61_ VNIVV 66_ VTLFC 71_ CQKGP 76_ KKVSS 81_ IYIFN 86_ LAVAD 91_ LLLLA 96_ TLPLW 101_ ATYYS 106_ YRYDW 111_ LFGPV 116_ MCKVF 121_ GSFLT 126_ LNMFA 131_ SIFFI 136_ TCMSV 141_ DRYQS 146_ VIYPF 151_ LSQRR 156_ NPWQA 161_ SYIVP 166_ LVWCM 171_ ACLSS 176_ LPTFY 181_ FRDVR 186_ TIEYL 191_ GVNAC 196_ IMAFP 201_ PEKYA 206_ QWSAG 211_ IALMK 216_ NILGF 221_ IIPLI 226_ FIATC 231_ YFGIR 236_ KHLLK 241_ TNSYG 246_ KNRIT 251_ RDQVL 256_ KMAAA 261_ VVLAF 266_ IICWL 271_ PFHVL 276_ TFLDA 281_ LAWMG 286_ VINSC 291_ EVIAV 296_ IDLAL 301_ PFAIL 306_ LGFTN 311_ SCVNP 316_ FLYCF 321_ VGNRF 326_ QQKLR 331_ SVFRV 336_ PITWL 341_ QGKRE 346_ SMSCR 351_ KSSSL 356_REMET
1: Receptor for angiotensin II, a vasoconstricting peptide (PubMed:28379944, PubMed:29967536, PubMed:31899086, PubMed:8185599). Signals primarily via a non-canonical G-protein- and beta-arrestin independent pathways (PubMed:28379944). Cooperates with MTUS1 to inhibit ERK2 activation and cell proliferation (PubMed:15123706)