Bis(5'-nucleosyl)-tetraphosphatase [asymmetrical] (EC 3.6.1.17) (Diadenosine 5',5'''-P1,P4-tetraphosphate asymmetrical hydrolase) (Ap4A hydrolase) (Ap4Aase) (Diadenosine tetraphosphatase) (Nucleoside diphosphate-linked moiety X motif 2) (Nudix motif 2)
1_MALRA 6_ CGLII 11_ FRRCL 16_ IPKVD 21_ NNAIE 26_ FLLLQ 31_ ASDGI 36_ HHWTP 41_ PKGHV 46_ EPGED 51_ DLETA 56_ LRETQ 61_ EEAGI 66_ EAGQL 71_ TIIEG 76_ FKREL 81_ NYVAR 86_ NKPKT 91_ VIYWL 96_ AEVKD 101_ YDVEI 106_ RLSHE 111_ HQAYR 116_ WLGLE 121_ EACQL 126_ AQFKE 131_ MKAAL 136_ QEGHQ 141_FLCSI
1: Catalyzes the asymmetric hydrolysis of diadenosine 5',5'''-P1,P4-tetraphosphate (Ap4A) to yield AMP and ATP (By similarity). Exhibits decapping activity towards FAD-capped RNAs and dpCoA-capped RNAs in vitro (By similarity)