Ras-related protein Rab-5C (EC 3.6.5.2) (L1880) (RAB5L)
1_MAGRG 6_ GAARP 11_ NGPAA 16_ GNKIC 21_ QFKLV 26_ LLGES 31_ AVGKS 36_ SLVLR 41_ FVKGQ 46_ FHEYQ 51_ ESTIG 56_ AAFLT 61_ QTVCL 66_ DDTTV 71_ KFEIW 76_ DTAGQ 81_ ERYHS 86_ LAPMY 91_ YRGAQ 96_ AAIVV 101_ YDITN 106_ TDTFA 111_ RAKNW 116_ VKELQ 121_ RQASP 126_ NIVIA 131_ LAGNK 136_ ADLAS 141_ KRAVE 146_ FQEAQ 151_ AYADD 156_ NSLLF 161_ METSA 166_ KTAMN 171_ VNEIF 176_ MAIAK 181_ KLPKN 186_ EPQNA 191_ TGAPG 196_ RNRGV 201_ DLQEN 206_ NPASR 211_SQCCS
1: The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different sets of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion