Cone cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha' (EC 3.1.4.35) (cGMP phosphodiesterase 6C)
1_MGEIN 6_ QVAVE 11_ KYLEE 16_ NPQFA 21_ KEYFD 26_ RKLRV 31_ EVLGE 36_ IFKNS 41_ QVPVQ 46_ SSMSF 51_ SELTQ 56_ VEESA 61_ LCLEL 66_ LWTVQ 71_ EEGGT 76_ PEQGV 81_ HRALQ 86_ RLAHL 91_ LQADR 96_ CSMFL 101_ CRSRN 106_ GIPEV 111_ ASRLL 116_ DVTPT 121_ SKFED 126_ NLVGP 131_ DKEVV 136_ FPLDI 141_ GIVGW 146_ AAHTK 151_ KTHNV 156_ PDVKK 161_ NSHFS 166_ DFMDK 171_ QTGYV 176_ TKNLL 181_ ATPIV 186_ VGKEV 191_ LAVIM 196_ AVNKV 201_ NASEF 206_ SKQDE 211_ EVFSK 216_ YLNFV 221_ SIILR 226_ LHHTS 231_ YMYNI 236_ ESRRS 241_ QILMW 246_ SANKV 251_ FEELT 256_ DVERQ 261_ FHKAL 266_ YTVRS 271_ YLNCE 276_ RYSIG 281_ LLDMT 286_ KEKEF 291_ YDEWP 296_ IKLGE 301_ VEPYK 306_ GPKTP 311_ DGREV 316_ NFYKI 321_ IDYIL 326_ HGKEE 331_ IKVIP 336_ TPPAD 341_ HWTLI 346_ SGLPT 351_ YVAEN 356_ GFICN 361_ MMNAP 366_ ADEYF 371_ TFQKG 376_ PVDET 381_ GWVIK 386_ NVLSL 391_ PIVNK 396_ KEDIV 401_ GVATF 406_ YNRKD 411_ GKPFD 416_ EHDEY 421_ ITETL 426_ TQFLG 431_ WSLLN 436_ TDTYD 441_ KMNKL 446_ ENRKD 451_ IAQEM 456_ LMNQT 461_ KATPE 466_ EIKSI 471_ LKFQE 476_ KLNVD 481_ VIDDC 486_ EEKQL 491_ VAILK 496_ EDLPD 501_ PRSAE 506_ LYEFR 511_ FSDFP 516_ LTEHG 521_ LIKCG 526_ IRLFF 531_ EINVV 536_ EKFKV 541_ PVEVL 546_ TRWMY 551_ TVRKG 556_ YRAVT 561_ YHNWR 566_ HGFNV 571_ GQTMF 576_ TLLMT 581_ GRLKK 586_ YYTDL 591_ EAFAM 596_ LAAAF 601_ CHDID 606_ HRGTN 611_ NLYQM 616_ KSTSP 621_ LARLH 626_ GSSIL 631_ ERHHL 636_ EYSKT 641_ LLQDE 646_ SLNIF 651_ QNLNK 656_ RQFET 661_ VIHLF 666_ EVAII 671_ ATDLA 676_ LYFKK 681_ RTMFQ 686_ KIVDA 691_ CEQMQ 696_ TEEEA 701_ IKYVT 706_ VDPTK 711_ KEIIM 716_ AMMMT 721_ ACDLS 726_ AITKP 731_ WEVQS 736_ QVALM 741_ VANEF 746_ WEQGD 751_ LERTV 756_ LQQQP 761_ IPMMD 766_ RNKRD 771_ ELPKL 776_ QVGFI 781_ DFVCT 786_ FVYKE 791_ FSRFH 796_ KEITP 801_ MLSGL 806_ QNNRV 811_ EWKSL 816_ ADEYD 821_ AKMKV 826_ IEEEA 831_ KKQEG 836_ GAEKA 841_ AEDSG 846_ GGDDK 851_KSKTC
1: As cone-specific cGMP phosphodiesterase, it plays an essential role in light detection and cone phototransduction by rapidly decreasing intracellular levels of cGMP