N-acylglucosamine 2-epimerase (AGE) (EC 5.1.3.8) (GlcNAc 2-epimerase) (N-acetyl-D-glucosamine 2-epimerase) (Renin-binding protein) (RnBP)
1_MSKGL 6_ PARQD 11_ MEKER 16_ ETLQA 21_ WKERV 26_ GQELD 31_ RVVAF 36_ WMEHS 41_ HDQEH 46_ GGFFT 51_ CLGRE 56_ GRVYD 61_ DLKYV 66_ WLQGR 71_ QVWMY 76_ CRLYR 81_ TFERF 86_ RHAQL 91_ LDAAK 96_ AGGEF 101_ LLRYA 106_ RVAPP 111_ GKKCA 116_ FVLTR 121_ DGRPV 126_ KVQRT 131_ IFSEC 136_ FYTMA 141_ MNELW 146_ RATGE 151_ VRYQT 156_ EAVEM 161_ MDQIV 166_ HWVQE 171_ DASGL 176_ GRPQL 181_ QGAPA 186_ AEPMA 191_ VPMML 196_ LNLVE 201_ QLGEA 206_ DEELA 211_ GKYAE 216_ LGDWC 221_ ARRIL 226_ QHVQR 231_ DGQAV 236_ LENVS 241_ EGGKE 246_ LPGCL 251_ GRQQN 256_ PGHTL 261_ EAGWF 266_ LLRHC 271_ IRKGD 276_ PELRA 281_ HVIDK 286_ FLLLP 291_ FHSGW 296_ DPDHG 301_ GLFYF 306_ QDADN 311_ FCPTQ 316_ LEWAM 321_ KLWWP 326_ HSEAM 331_ IAFLM 336_ GYSDS 341_ GDPVL 346_ LRLFY 351_ QVAEY 356_ TFRQF 361_ RDPEY 366_ GEWFG 371_ YLSRE 376_ GKVAL 381_ SIKGG 386_ PFKGC 391_ FHVPR 396_ CLAMC 401_ EEMLG 406_ ALLSR 411_ PAPAP 416_ SPAPT 421_PACRG
1: Catalyzes the interconversion of N-acetylglucosamine to N-acetylmannosamine (PubMed:10502668, PubMed:12499362, PubMed:9990133). Involved in the N-glycolylneuraminic acid (Neu5Gc) degradation pathway: although human is not able to catalyze formation of Neu5Gc due to the inactive CMAHP enzyme, Neu5Gc is present in food and must be degraded (PubMed:9990133)