Aldehyde dehydrogenase family 3 member A2 (EC 1.2.1.3) (EC 1.2.1.94) (Aldehyde dehydrogenase 10) (Fatty aldehyde dehydrogenase) (Microsomal aldehyde dehydrogenase)
1_MELEV 6_ RRVRQ 11_ AFLSG 16_ RSRPL 21_ RFRLQ 26_ QLEAL 31_ RRMVQ 36_ EREKD 41_ ILTAI 46_ AADLC 51_ KSEFN 56_ VYSQE 61_ VITVL 66_ GEIDF 71_ MLENL 76_ PEWVT 81_ AKPVK 86_ KNVLT 91_ MLDEA 96_ YIQPQ 101_ PLGVV 106_ LIIGA 111_ WNYPF 116_ VLTIQ 121_ PLIGA 126_ IAAGN 131_ AVIIK 136_ PSELS 141_ ENTAK 146_ ILAKL 151_ LPQYL 156_ DQDLY 161_ IVING 166_ GVEET 171_ TELLK 176_ QRFDH 181_ IFYTG 186_ NTAVG 191_ KIVME 196_ AAAKH 201_ LTPVT 206_ LELGG 211_ KSPCY 216_ IDKDC 221_ DLDIV 226_ CRRIT 231_ WGKYM 236_ NCGQT 241_ CIAPD 246_ YILCE 251_ ASLQN 256_ QIVWK 261_ IKETV 266_ KEFYG 271_ ENIKE 276_ SPDYE 281_ RIINL 286_ RHFKR 291_ ILSLL 296_ EGQKI 301_ AFGGE 306_ TDEAT 311_ RYIAP 316_ TVLTD 321_ VDPKT 326_ KVMQE 331_ EIFGP 336_ ILPIV 341_ PVKNV 346_ DEAIN 351_ FINER 356_ EKPLA 361_ LYVFS 366_ HNHKL 371_ IKRMI 376_ DETSS 381_ GGVTG 386_ NDVIM 391_ HFTLN 396_ SFPFG 401_ GVGSS 406_ GMGAY 411_ HGKHS 416_ FDTFS 421_ HQRPC 426_ LLKSL 431_ KREGA 436_ NKLRY 441_ PPNSQ 446_ SKVDW 451_ GKFFL 456_ LKRFN 461_ KEKLG 466_ LLLLT 471_ FLGIV 476_AAVLV
1: Catalyzes the oxidation of medium and long chain aliphatic aldehydes to fatty acids. Active on a variety of saturated and unsaturated aliphatic aldehydes between 6 and 24 carbons in length (PubMed:18035827, PubMed:18182499, PubMed:22633490, PubMed:25047030, PubMed:9133646, PubMed:9662422). Responsible for conversion of the sphingosine 1-phosphate (S1P) degradation product hexadecenal to hexadecenoic acid (PubMed:22633490)