26S proteasome non-ATPase regulatory subunit 7 (26S proteasome regulatory subunit RPN8) (26S proteasome regulatory subunit S12) (Mov34 protein homolog) (Proteasome subunit p40)
1_MPELA 6_ VQKVV 11_ VHPLV 16_ LLSVV 21_ DHFNR 26_ IGKVG 31_ NQKRV 36_ VGVLL 41_ GSWQK 46_ KVLDV 51_ SNSFA 56_ VPFDE 61_ DDKDD 66_ SVWFL 71_ DHDYL 76_ ENMYG 81_ MFKKV 86_ NARER 91_ IVGWY 96_ HTGPK 101_ LHKND 106_ IAINE 111_ LMKRY 116_ CPNSV 121_ LVIID 126_ VKPKD 131_ LGLPT 136_ EAYIS 141_ VEEVH 146_ DDGTP 151_ TSKTF 156_ EHVTS 161_ EIGAE 166_ EAEEV 171_ GVEHL 176_ LRDIK 181_ DTTVG 186_ TLSQR 191_ ITNQV 196_ HGLKG 201_ LNSKL 206_ LDIRS 211_ YLEKV 216_ ATGKL 221_ PINHQ 226_ IIYQL 231_ QDVFN 236_ LLPDV 241_ SLQEF 246_ VKAFY 251_ LKTND 256_ QMVVV 261_ YLASL 266_ IRSVV 271_ ALHNL 276_ INNKI 281_ ANRDA 286_ EKKEG 291_ QEKEE 296_ SKKDR 301_ KEDKE 306_ KDKDK 311_ EKSDV 316_KKEEK
1: Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair