C-C chemokine receptor type 5 (C-C CKR-5) (CC-CKR-5) (CCR-5) (CCR5) (CHEMR13) (HIV-1 fusion coreceptor) (CD antigen CD195)
1_MDYQV 6_ SSPIY 11_ DINYY 16_ TSEPC 21_ QKINV 26_ KQIAA 31_ RLLPP 36_ LYSLV 41_ FIFGF 46_ VGNML 51_ VILIL 56_ INCKR 61_ LKSMT 66_ DIYLL 71_ NLAIS 76_ DLFFL 81_ LTVPF 86_ WAHYA 91_ AAQWD 96_ FGNTM 101_ CQLLT 106_ GLYFI 111_ GFFSG 116_ IFFII 121_ LLTID 126_ RYLAV 131_ VHAVF 136_ ALKAR 141_ TVTFG 146_ VVTSV 151_ ITWVV 156_ AVFAS 161_ LPGII 166_ FTRSQ 171_ KEGLH 176_ YTCSS 181_ HFPYS 186_ QYQFW 191_ KNFQT 196_ LKIVI 201_ LGLVL 206_ PLLVM 211_ VICYS 216_ GILKT 221_ LLRCR 226_ NEKKR 231_ HRAVR 236_ LIFTI 241_ MIVYF 246_ LFWAP 251_ YNIVL 256_ LLNTF 261_ QEFFG 266_ LNNCS 271_ SSNRL 276_ DQAMQ 281_ VTETL 286_ GMTHC 291_ CINPI 296_ IYAFV 301_ GEKFR 306_ NYLLV 311_ FFQKH 316_ IAKRF 321_ CKCCS 326_ IFQQE 331_ APERA 336_ SSVYT 341_ RSTGE 346_QEISV
1: Receptor for a number of inflammatory CC-chemokines including CCL3/MIP-1-alpha, CCL4/MIP-1-beta and RANTES and subsequently transduces a signal by increasing the intracellular calcium ion level. May play a role in the control of granulocytic lineage proliferation or differentiation. Participates in T-lymphocyte migration to the infection site by acting as a chemotactic receptor (PubMed:30713770)
2: (Microbial infection) Acts as a coreceptor (CD4 being the primary receptor) of human immunodeficiency virus-1/HIV-1