Rho GDP-dissociation inhibitor 2 (Rho GDI 2) (Ly-GDI) (Rho-GDI beta)
1_MTEKA 6_ PEPHV 11_ EEDDD 16_ DELDS 21_ KLNYK 26_ PPPQK 31_ SLKEL 36_ QEMDK 41_ DDESL 46_ IKYKK 51_ TLLGD 56_ GPVVT 61_ DPKAP 66_ NVVVT 71_ RLTLV 76_ CESAP 81_ GPITM 86_ DLTGD 91_ LEALK 96_ KETIV 101_ LKEGS 106_ EYRVK 111_ IHFKV 116_ NRDIV 121_ SGLKY 126_ VQHTY 131_ RTGVK 136_ VDKAT 141_ FMVGS 146_ YGPRP 151_ EEYEF 156_ LTPVE 161_ EAPKG 166_ MLARG 171_ TYHNK 176_ SFFTD 181_ DDKQD 186_ HLSWE 191_ WNLSI 196_KKEWT
1: Regulates the GDP/GTP exchange reaction of the Rho proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP to them (PubMed:7512369, PubMed:8356058). Regulates reorganization of the actin cytoskeleton mediated by Rho family members (PubMed:8262133)