Ephrin-A4 (EPH-related receptor tyrosine kinase ligand 4) (LERK-4)
1_MRLLP 6_ LLRTV 11_ LWAAF 16_ LGSPL 21_ RGGSS 26_ LRHVV 31_ YWNSS 36_ NPRLL 41_ RGDAV 46_ VELGL 51_ NDYLD 56_ IVCPH 61_ YEGPG 66_ PPEGP 71_ ETFAL 76_ YMVDW 81_ PGYES 86_ CQAEG 91_ PRAYK 96_ RWVCS 101_ LPFGH 106_ VQFSE 111_ KIQRF 116_ TPFSL 121_ GFEFL 126_ PGETY 131_ YYISV 136_ PTPES 141_ SGQCL 146_ RLQVS 151_ VCCKE 156_ RKSES 161_ AHPVG 166_ SPGES 171_ GTSGW 176_ RGGDT 181_ PSPLC 186_ LLLLL 191_ LLLIL 196_RLLRI
1: Cell surface GPI-bound ligand for Eph receptors, a family of receptor tyrosine kinases which are crucial for migration, repulsion and adhesion during neuronal, vascular and epithelial development. Binds promiscuously Eph receptors residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. May play a role in the interaction between activated B-lymphocytes and dendritic cells in tonsils