Gene name: MRPL12

Uniprot entry:

P52815

Protein names:

39S ribosomal protein L12, mitochondrial (L12mt) (MRP-L12) (5c5-2) (Mitochondrial large ribosomal subunit protein bL12m)

Protein sequence:

1_MLPAA 6_ ARPLW 11_ GPCLG 16_ LRAAA 21_ FRLAR 26_ RQVPC 31_ VCAVR 36_ HMRSS 41_ GHQRC 46_ EALAG 51_ APLDN 56_ APKEY 61_ PPKIQ 66_ QLVQD 71_ IASLT 76_ LLEIS 81_ DLNEL 86_ LKKTL 91_ KIQDV 96_ GLVPM 101_ GGVMS 106_ GAVPA 111_ AAAQE 116_ AVEED 121_ IPIAK 126_ ERTHF 131_ TVRLT 136_ EAKPV 141_ DKVKL 146_ IKEIK 151_ NYIQG 156_ INLVQ 161_ AKKLV 166_ ESLPQ 171_ EIKAN 176_ VAKAE 181_ AEKIK 186_ AALEA 191_VGGTV

Protein annotations

Protein functions:

1: As a component of the mitochondrial large ribosomal subunit, plays a role in mitochondrial translation (PubMed:23603806). When present in mitochondria as a free protein not associated with the ribosome, associates with mitochondrial RNA polymerase POLRMT to activate transcription (PubMed:22003127). Required for POLRMT stability (PubMed:26586915)