Geranylgeranyl transferase type-1 subunit beta (EC 2.5.1.59) (Geranylgeranyl transferase type I subunit beta) (GGTase-I-beta) (Type I protein geranyl-geranyltransferase subunit beta)
1_MAATE 6_ DERLA 11_ GSGEG 16_ ERLDF 21_ LRDRH 26_ VRFFQ 31_ RCLQV 36_ LPERY 41_ SSLET 46_ SRLTI 51_ AFFAL 56_ SGLDM 61_ LDSLD 66_ VVNKD 71_ DIIEW 76_ IYSLQ 81_ VLPTE 86_ DRSNL 91_ NRCGF 96_ RGSSY 101_ LGIPF 106_ NPSKA 111_ PGTAH 116_ PYDSG 121_ HIAMT 126_ YTGLS 131_ CLVIL 136_ GDDLS 141_ RVNKE 146_ ACLAG 151_ LRALQ 156_ LEDGS 161_ FCAVP 166_ EGSEN 171_ DMRFV 176_ YCASC 181_ ICYML 186_ NNWSG 191_ MDMKK 196_ AITYI 201_ RRSMS 206_ YDNGL 211_ AQGAG 216_ LESHG 221_ GSTFC 226_ GIASL 231_ CLMGK 236_ LEEVF 241_ SEKEL 246_ NRIKR 251_ WCIMR 256_ QQNGY 261_ HGRPN 266_ KPVDT 271_ CYSFW 276_ VGATL 281_ KLLKI 286_ FQYTN 291_ FEKNR 296_ NYILS 301_ TQDRL 306_ VGGFA 311_ KWPDS 316_ HPDAL 321_ HAYFG 326_ ICGLS 331_ LMEES 336_ GICKV 341_ HPALN 346_ VSTRT 351_ SERLL 356_ DLHQS 361_ WKTKD 366_ SKQCS 371_ENVHI
1: Catalyzes the transfer of a geranyl-geranyl moiety from geranyl-geranyl pyrophosphate to a cysteine at the fourth position from the C-terminus of proteins having the C-terminal sequence Cys-aliphatic-aliphatic-X. Known substrates include RAC1, RAC2, RAP1A and RAP1B