Gene name: AP3M2

Uniprot entry:

P53677

Protein names:

AP-3 complex subunit mu-2 (Adaptor-related protein complex 3 subunit mu-2) (Clathrin assembly protein assembly protein complex 3 mu-2 medium chain) (Clathrin coat assembly protein AP47 homolog 2) (Clathrin coat-associated protein AP47 homolog 2) (Golgi adaptor AP-1 47 kDa protein homolog 2) (HA1 47 kDa subunit homolog 2) (Mu3B-adaptin) (P47B)

Protein sequence:

1_MIHSL 6_ FLINS 11_ SGDIF 16_ LEKHW 21_ KSVVS 26_ RSVCD 31_ YFFEA 36_ QERAT 41_ EAENV 46_ PPVIP 51_ TPHHY 56_ LLSVY 61_ RHKIF 66_ FVAVI 71_ QTEVP 76_ PLFVI 81_ EFLHR 86_ VVDTF 91_ QDYFG 96_ VCSEP 101_ VIKDN 106_ VVVVY 111_ EVLEE 116_ MLDNG 121_ FPLAT 126_ ESNIL 131_ KELIK 136_ PPTIL 141_ RTVVN 146_ TITGS 151_ TNVGD 156_ QLPTG 161_ QLSVV 166_ PWRRT 171_ GVKYT 176_ NNEAY 181_ FDVIE 186_ EIDAI 191_ IDKSG 196_ STITA 201_ EIQGV 206_ IDACV 211_ KLTGM 216_ PDLTL 221_ SFMNP 226_ RLLDD 231_ VSFHP 236_ CVRFK 241_ RWESE 246_ RILSF 251_ IPPDG 256_ NFRLL 261_ SYHVS 266_ AQNLV 271_ AIPVY 276_ VKHNI 281_ SFRDS 286_ SSLGR 291_ FEITV 296_ GPKQT 301_ MGKTI 306_ EGVTV 311_ TSQMP 316_ KGVLN 321_ MSLTP 326_ SQGTH 331_ TFDPV 336_ TKMLS 341_ WDVGK 346_ INPQK 351_ LPSLK 356_ GTMSL 361_ QAGAS 366_ KPDEN 371_ PTINL 376_ QFKIQ 381_ QLAIS 386_ GLKVN 391_ RLDMY 396_ GEKYK 401_ PFKGI 406_ KYMTK 411_AGKFQ

Protein annotations

Protein functions:

1: Part of the AP-3 complex, an adaptor-related complex which is not clathrin-associated. The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane and may be directly involved in trafficking to lysosomes. In concert with the BLOC-1 complex, AP-3 is required to target cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals