Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A (Cam-PDE 1A) (EC 3.1.4.17) (61 kDa Cam-PDE) (hCam-1)
1_MGSSA 6_ TEIEE 11_ LENTT 16_ FKYLT 21_ GEQTE 26_ KMWQR 31_ LKGIL 36_ RCLVK 41_ QLERG 46_ DVNVV 51_ DLKKN 56_ IEYAA 61_ SVLEA 66_ VYIDE 71_ TRRLL 76_ DTEDE 81_ LSDIQ 86_ TDSVP 91_ SEVRD 96_ WLAST 101_ FTRKM 106_ GMTKK 111_ KPEEK 116_ PKFRS 121_ IVHAV 126_ QAGIF 131_ VERMY 136_ RKTYH 141_ MVGLA 146_ YPAAV 151_ IVTLK 156_ DVDKW 161_ SFDVF 166_ ALNEA 171_ SGEHS 176_ LKFMI 181_ YELFT 186_ RYDLI 191_ NRFKI 196_ PVSCL 201_ ITFAE 206_ ALEVG 211_ YSKYK 216_ NPYHN 221_ LIHAA 226_ DVTQT 231_ VHYIM 236_ LHTGI 241_ MHWLT 246_ ELEIL 251_ AMVFA 256_ AAIHD 261_ YEHTG 266_ TTNNF 271_ HIQTR 276_ SDVAI 281_ LYNDR 286_ SVLEN 291_ HHVSA 296_ AYRLM 301_ QEEEM 306_ NILIN 311_ LSKDD 316_ WRDLR 321_ NLVIE 326_ MVLST 331_ DMSGH 336_ FQQIK 341_ NIRNS 346_ LQQPE 351_ GIDRA 356_ KTMSL 361_ ILHAA 366_ DISHP 371_ AKSWK 376_ LHYRW 381_ TMALM 386_ EEFFL 391_ QGDKE 396_ AELGL 401_ PFSPL 406_ CDRKS 411_ TMVAQ 416_ SQIGF 421_ IDFIV 426_ EPTFS 431_ LLTDS 436_ TEKIV 441_ IPLIE 446_ EASKA 451_ ETSSY 456_ VASSS 461_ TTIVG 466_ LHIAD 471_ ALRRS 476_ NTKGS 481_ MSDGS 486_ YSPDY 491_ SLAAV 496_ DLKSF 501_ KNNLV 506_ DIIQQ 511_ NKERW 516_ KELAA 521_ QEART 526_SSQKC
1: Calcium/calmodulin-dependent cyclic nucleotide phosphodiesterase with a dual specificity for the second messengers cGMP and cAMP, which are key regulators of many important physiological processes. Has a higher efficiency with cGMP compared to cAMP