Allograft inflammatory factor 1 (AIF-1) (Ionized calcium-binding adapter molecule 1) (Protein G1)
1_MSQTR 6_ DLQGG 11_ KAFGL 16_ LKAQQ 21_ EERLD 26_ EINKQ 31_ FLDDP 36_ KYSSD 41_ EDLPS 46_ KLEGF 51_ KEKYM 56_ EFDLN 61_ GNGDI 66_ DIMSL 71_ KRMLE 76_ KLGVP 81_ KTHLE 86_ LKKLI 91_ GEVSS 96_ GSGET 101_ FSYPD 106_ FLRMM 111_ LGKRS 116_ AILKM 121_ ILMYE 126_ EKARE 131_ KEKPT 136_ GPPAK 141_KAISE
1: Actin-binding protein that enhances membrane ruffling and RAC activation. Enhances the actin-bundling activity of LCP1. Binds calcium. Plays a role in RAC signaling and in phagocytosis. May play a role in macrophage activation and function. Promotes the proliferation of vascular smooth muscle cells and of T-lymphocytes. Enhances lymphocyte migration. Plays a role in vascular inflammation